Results 171 to 180 of about 29,539 (245)

Systematic review: Safety and efficacy of atomoxetine in children and adolescents with autism spectrum disorder

JCPP Advances, Volume 6, Issue 1, March 2026.
This systematic review aimed to assess the current evidence on the efficacy and safety of Atomoxetine in common clinical symptoms of autism spectrum disorder (ASD) for children and adolescents. With limited studies available, there is a need for more high‐power studies for the use of Atomoxetine in children and adolescents with autism spectrum disorder.
Nihit Gupta, Daniel Boyes, Hunter Hanlon‐Taylor, Mayank Gupta   +3 more
wiley   +1 more source

Intrathecal idursulfase‐IT in children younger than 3 years with neuronopathic mucopolysaccharidosis II in a single‐arm, open‐label, phase 2/3 substudy and extension

JIMD Reports, Volume 67, Issue 2, March 2026.
Abstract Data from a phase 2/3, randomized, controlled, open‐label, multicenter trial in children with neuronopathic mucopolysaccharidosis II (MPS II; Hunter syndrome) older than 3 years suggested a benefit of intrathecal idursulfase‐IT on cognitive functioning in some patients. We describe a separate, parallel, open‐label, single‐arm, 52‐week substudy
Joseph Muenzer, Barbara K. Burton, Paul Harmatz, Luis González Gutiérrez‐Solana, Matilde Ruiz‐Garcia, Simon A. Jones, Nathalie Guffon, Michal Inbar‐Feigenberg, Drago Bratkovic, Stewart Rust, Michael Hale, Yuna Wu, Karen S. Yee, David A. H. Whiteman, David Alexanderian   +14 more
wiley   +1 more source

Why We Do Not Recommend That People With High‐Risk Smoldering Myeloma Receive Treatment

American Journal of Hematology, Volume 101, Issue 3, Page 409-412, March 2026.
Ghulam Rehman Mohyuddin, Mackenzie Lemieux, Rajshekhar Chakraborty, Morie Gertz   +3 more
wiley   +1 more source

Vascular Reconstruction in Extremity Soft Tissue Sarcomas: A Systematic Review and Single‐Arm Meta‐Analysis

Journal of Surgical Oncology, Volume 133, Issue 4, Page 486-510, March 15, 2026.
ABSTRACT Introduction The management of extremity soft tissue sarcomas (STS) involving major vessels presents unique challenges, historically leading to amputation. Advances in vascular reconstruction have enabled limb‐sparing surgery (LSS), but outcomes and perioperative risks remain uncertain.
Lucas Monteiro Delgado, Bernardo Fontel Pompeu, Vinícius dos Santos Macedo, Gabriel Henrique Acedo Martins, Eric Pasqualotto, Matheus Reginato Araujo, Julia Hoici Brunini, Victor Andrade Nunes, Cláudia Theis, Samuel Aguiar Junior   +9 more
wiley   +1 more source

Varicella Zoster Virus Infection: Clinical Features, Molecular Pathogenesis, Treatment, and Prevention

MedComm, Volume 7, Issue 3, March 2026.
This review focuses on the clinical features, molecular mechanisms, treatment methods, and preventive measures of the VZV, with the aim of providing a theoretical basis for the development of new treatment and prevention methods for HZ. ABSTRACT Varicella zoster virus (VZV) is a ubiquitous human herpesvirus that establishes lifelong latency and causes ...
Lei Peng, Honghao Song, Tianying Li, Yuqing Ma, Chen Yan, Yuhan Cao, Kaiqiang Sun, Chaofeng Han, Hongbin Yuan   +8 more
wiley   +1 more source

Migration, Stretched Households and the Loneliness of Older Adults in South Africa

Population, Space and Place, Volume 32, Issue 2, March 2026.
ABSTRACT This study contributes to the literature on out‐migration and the social connectedness of older adults who remain “left behind”. It investigates the loneliness reports of older African adults in the South African context, where out‐migrants are reported as retaining membership in their household of origin.
Dorrit Posel
wiley   +1 more source

Management and Biosecurity Practices of Pig Farms in Nepal

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
1) Biosecurity adoption level of pig farmers in Nepal is low. 2) The pig farms are highly vulnerable to infectious diseases like African swine fever. 3) Governments of Nepal should take immediate actions focusing on capacity building of pig farmers, information dissemination and adoption of biosecurity practices.
Sachin Shrestha, Alok Dhakal, Ramjee Ghimire, Min Bahadur Oli, Rakesh Kumar Yadav, Nishant Shah   +5 more
wiley   +1 more source

Diagnosis and follow-up of patients with Hunter syndrome in Spain: A Delphi consensus. [PDF]

Medicine (Baltimore), 2018
González-Gutiérrez-Solana L, Guillén-Navarro E, Del Toro M, Dalmau J, González-Meneses A, Couce ML.   +5 more
europepmc   +1 more source

Connecting the Dots: A Semantic Network Approach to Pediatric iNO Research Discovery

WIREs Data Mining and Knowledge Discovery, Volume 16, Issue 1, March 2026.
Semantic Reconstruction of Pediatric iNO Research: From Lexical Networks to Translational Insight. This graphical abstract summarizes a computational framework used to map the historical and semantic evolution of inhaled nitric oxide (iNO) research in pediatric cardiac surgery.
S. Fernando Gomes Jr, Paulo Cesar Duarte Junior, Shirley Ferraz Crispilho, Hafsa Siddiqui, Jaciara Santos, Kaushik Pal, Aron José Pazin de Andrade, Himanshu Upadhyay   +7 more
wiley   +1 more source

Drug Delivery Systems for Resiquimod to Control Myeloid‐Derived Suppressor Cells in Cancer Immunotherapy

WIREs Nanomedicine and Nanobiotechnology, Volume 18, Issue 2, March/April 2026.
Myeloid‐derived suppressor cells (MDSCs) are key contributors to cancer immunotherapy failure and major targets in new therapeutic strategies. We highlight therapeutic approaches to counteract their immunosuppressive functions and discuss recent efforts to optimize drug delivery for controlling MDSCs, focusing on resiquimod as a representative drug ...
Yanying He, Yoon Yeo
wiley   +1 more source