Results 221 to 230 of about 77,921 (314)

T-cadherin deprivation in endothelial cells promotes vascular injury in Kawasaki disease through SOD2/ROS/NLRP3 pathway-mediated pyroptosis. [PDF]

J Mol Cell Biol
Lin Y, Wang F, Luo X, Yang X, Yang W, Lu Z, Wang Z, Zhou H, Ruan M, Chen K, Fu L, Pi L, Che D, Yu H, Gu X.   +14 more
europepmc   +1 more source

KAT2A Promotes the Progression of Renal Cell Carcinoma by Regulating the Succinylation of SERPINE2

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Epithelial‐mesenchymal transition (EMT) and angiogenesis are critical drivers of renal cell carcinoma (RCC) progression, yet their upstream regulatory mechanisms remain incompletely understood. This study aimed to investigate the role of KAT2A in RCC and elucidate the underlying molecular mechanism by which it promotes tumor progression.
Chang‐Cheng Liu, Xue‐Dong Li
wiley   +1 more source

Untargeted metabolomics reveals the effect of MYH9 on the metabolism of vascular endothelial cells. [PDF]

iScience
Yuan R, Guo L, Song H, Zhang X, Wang M, Wang X.   +5 more
europepmc   +1 more source

Endothelial Hydrogels Improve Microvascular Regeneration and Perfusion in Tracheal Scaffolds

The Laryngoscope, EarlyView.
Insufficient vascularization remains a major barrier to successful tracheal transplantation. This study demonstrates that an endothelial hydrogel significantly enhances graft perfusion and neovessel organization compared to non‐endothelial hydrogel controls.
Molly O. Hunter, Lumei Liu, Nathaniel Hochuli, Olivia Chan, Jazmin Calyeca, Ada C. Sher, Tendy Chiang   +6 more
wiley   +1 more source

Bioinformatic Analysis and Experimental Verification Reveal the Protective Role of Baicalein Against LPS-Induced Endothelial Cell Dysfunction. [PDF]

J Inflamm Res
Luo F, Ao J, Chen Y, Cui Y, Gan X, Li M.
europepmc   +1 more source

Convergence of Organ‐on‐a‐Chip and Freeform Printing of Sacrificial Poly(2‐cyclopropyl‐2‐oxazoline) Enables the Generation of Perfusable Endothelialized Channels in Hydrogels

Macromolecular Rapid Communications, EarlyView.
We employ freeform printing of thermo‐responsive poly(2‐oxazoline) to directly fabricate suspended sacrificial vascular templates within Organ‐on‐a‐chip devices. This enables circular, perfusable channels down to 200 µm without post‐processing.
Giulia Maria Di Gravina, Patrick Kuntschke, Zeno Guttenberg, Philipp Linke, Katja P. Schumann, Meike N. Leiske, Thomas Scheibel, Matthias Ryma   +7 more
wiley   +1 more source

Circulating placental small extracellular vesicles miR-2110 depletion drives maternal-fetal endothelial injury in preeclampsia. [PDF]

Cell Commun Signal
Wang Y, Lin Q, Li R, Yu J, Xie L, Wang S, Pan K, Li Y, Cao J, Chang Y, Li Z.   +10 more
europepmc   +1 more source

On the Assembly of Actin Polymerization‐Powered Motors

Macromolecular Rapid Communications, EarlyView.
Actin polymerization‐powered motors have the highest speed when the actin recruiting‐polymerizing proteins are immobilized in polymer brushes on their surface. These motors orbit around larger tracer particles at pH above the isoelectric point of ActA but dock onto the tracer particles’ surface at lower pH. ABSTRACT Nano‐ and micromotors are a class of
Miguel A. Ramos Docampo, Cathrine Abild Meyer, Brigitte Städler   +2 more
wiley   +1 more source

LXW7 Peptide Modification of Acellular Liver Scaffolds Improves Endothelialization and Hemocompatibility in Bioengineered Liver. [PDF]

J Funct Biomater
Yadav U, Yadav CJ, Afrin S, Lee JY, Kamel J, Park KM.   +5 more
europepmc   +1 more source

Harnessing Phytochemicals for Brain Cancer Therapy: Insights Into Medulloblastoma and Glioblastoma Treatment

Phytochemical Analysis, EarlyView.
ABSTRACT Primary brain tumors are life‐threatening diseases. Glioblastoma is the most aggressive type with a poor prognosis. Medulloblastoma is the most common pediatric brain tumor. While surgical treatments often result in recurrences owing to the complex nature of the tumor microenvironment, conventional treatments lower the quality of life of ...
Ilkay Irem Ozbek, Mesra Aktas, Hale Saybasili, Kutlu O. Ulgen   +3 more
wiley   +1 more source