Results 241 to 250 of about 77,921 (314)

Space biomedicine‐oriented bioink and biomimetic blood‒brain barrier

VIEW, EarlyView.
Bioinks and bioprinting play a pivotal role in the successful delivery of cell models and the fabrication of tissue models for space biomedicine research. This study investigated the effects of hypergravity and vibration on two‐dimensional adherent cells and three‐dimensional embedded cells and provided methods for storing hybrid bioink and high ...
Ranran Yan, Ge Gao, YuJuan Li, YuLin Deng   +3 more
wiley   +1 more source

Extracellular Vesicles Derived from VEGF mRNA-Engineered Mesenchymal Stem Cells Promote Endothelial Cell Survival. [PDF]

Cells
Zhang C, Huang P, Pak M, Korchak JA, Zubair AC.   +4 more
europepmc   +1 more source

Metabolic engineering of adipose‐derived stem cell exosomes via arachidonic acid potentiates diabetic wound repair by orchestrating angiogenesis: A multi‐omics guided strategy

VIEW, EarlyView.
AA‐Exos promotes angiogenesis and accelerates diabetic wound healing by activating the PI3K/AKT/mTOR pathway. Abstract Diabetic wounds are common and challenging complications of diabetes, characterized by delayed healing and an increased risk of infection.
Yujiao Cai, Jinnan Wang, Yan Liu, Xiaoke Zhu, Zhanyuan Yuan, Weiling Li, Dehui Che, Dongsheng Cao   +7 more
wiley   +1 more source

COPD airway epithelial cells-derived extracellular vesicles contribute to endothelial dysfunction and atherosclerosis via the miR-141-3p/PDCD4 axis. [PDF]

J Nanobiotechnology
Wang Z, Shi J, Liang Y, Li D, Luo Y, Zhang Y, Chen Y, Li N, Gai X, Sun Y.   +9 more
europepmc   +1 more source

Decreased Production of Tissue Plasminogen Activator in Endothelial Cells From Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Introduction Previous studies have demonstrated that chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by excessive fibrin deposition which is related to impaired production of tissue plasminogen activator(t‐PA) by epithelial cells.
Qian‐Qian Zhang, Chen Zhang, Jia‐Ni Chen, Fu‐Ying Cheng, Yi‐Zhang Wang, Shi‐Rui Xue, Huan Wang, De‐Hui Wang, Xi‐Cai Sun, Li Hu   +9 more
wiley   +1 more source

Expression of IMD-CBM peptide induces the autophagic degradation of CAV1 (caveolin 1) to inhibit LDL transcytosis and retard diabetic atherosclerosis. [PDF]

Autophagy
Wang L, Jia X, Bai X, Zhao Y, Cheng W, Shu M, Shu Y, Zhang L, Wang R, Jin S.   +9 more
europepmc   +1 more source

Identification of Autologous Tissue Sources and Optimization of a Treatment Method for Intraoperative Manufacturing of Heart Valve Constructs

Artificial Organs, EarlyView.
The use of autologous connective tissue, such as pericardium or peritoneum, combined with controlled tissue treatment, has the potential to result in a more durable heart valve prosthesis than current commercial prostheses. ABSTRACT Introduction Valvular heart disease remains a leading cause of morbidity and mortality. Current biological and mechanical
Marvin Steitz, Mahamuda Badhon Khan, Katharina Fritsch, Alexander Breitenstein‐Attach, Jana Katharina Betty Korbacher, Jordi Joaquin Modolell Y Mainou, Katrin Schrimpf, Robert Ramm, Sara Knigge, Katja Eildermann, Georg Arlt, Antonia Schulz, Jonathan Frederik Sebastian Kiekenap, Boris Warnack, Peter Kramer, Frank Edelmann, Felix Berger, Boris Schmitt   +17 more
wiley   +1 more source

VE-cadherin interaction proteomics identifies ARVCF as stabilizer of endothelial adherens junctions. [PDF]

iScience
Schoon RM, van Krimpen-Malinova TS, de Heer I, Hoogendijk AJ, van Alphen FPJ, de Haan A, van Stalborch AD, Tol S, van Buul JD, van den Biggelaar M, Huveneers S.   +10 more
europepmc   +1 more source

Inhibition of Fibroblast Activation Protein‐α Ameliorates Intervertebral Disc Degeneration via Reduced Vascular Invasion in Cartilage Endplate

Cell Proliferation, EarlyView.
Schematic illustration showing that FAP‐α promoted angiogenesis, cytokine release and ECM degradation in the CEP degeneration of the intervertebral disc through upregulating the PI3K/Akt/HIF‐1α/VEGFA pathway. ABSTRACT Intervertebral disc degeneration (IDD) is a primary cause of low back pain, with the development of new blood vessels being a key ...
Hao‐Wei Xu, Sheng‐Jie Chang, Shuo Wang, Xiao‐Wei Liu, Shan‐Jin Wang   +4 more
wiley   +1 more source

Stage‐Associated Microglial Subpopulations and Dynamics in Vascular Pathogenesis of Oxygen‐Induced Retinopathy

Cell Proliferation, EarlyView.
In the oxygen‐induced retinopathy (OIR) mouse model, two distinct microglial subpopulations play opposing roles: highly glycolytic microglia (HGM) promote neovascular formation via Pkm2, while Mrc1/CD206‐positive phagocytosis‐associated microglia (PAM) facilitate its regression.
Yuan Ma, Ziye Chen, Baoyi Liu, Wen Ding, Runping Duan, Kangjie Kong, Zhuojun Xu, Jizhu Li, Jiali Ru, Dianlei Guo, Xiaoyue Wei, Yaping Liu, Zhuangling Lin, Yang Meng, Yuan Liu, Lan Jiang, Zitong Chen, Rebiya Tuxun, Chinling Tsai, Chunqiao Liu, Tao Li   +20 more
wiley   +1 more source