Results 271 to 280 of about 77,921 (314)

The effects of cadmium on VEGF‐mediated angiogenesis in HUVECs

Journal of Applied Toxicology, 2011
ABSTRACTCadmium (Cd) is a highly toxic element that causes morphologic alterations and dysfunction in blood vessels. The altered vascular function caused by cadmium has been implicated in a range of chronic diseases, including hypertension. The effects of cadmium are a multisystem phenomenon involving inflammation, hypertrophy, apoptosis, angiogenesis ...
Jisun, Kim, Wonbong, Lim, Youngjong, Ko, Hyukil, Kwon, Sangwoo, Kim, Oksu, Kim, Gyeongju, Park, Hongran, Choi, Okjoon, Kim   +8 more
openaire   +2 more sources

Efficacy of IKVAV Peptide on HUVEC Microtissue Growth

2018 Medical Technologies National Congress (TIPTEKNO), 2018
The extracellular matrix (ECM) structure of the three-dimensional (3D) network of cells in body play an important role in cellular events. Cell-cell and cell-matrix interactions can be achieved in 3D cell culture systems as in vivo systems. For this reason, the loss of cell functions is less in 3D cultures than in two dimensional systems.
Koken, Betul, Yarali, Ziysan Buse, Karaman, Ozan   +2 more
openaire   +2 more sources

Halofuginone inhibits LPS-induced attachment of monocytes to HUVECs

International Immunopharmacology, 2020
Atherosclerosis has become a major cause of mortality for several years, however the underlying mechanism of this disorder is still complicated. Endothelial dysfunction is a hallmark in the beginning of atherosclerosis. Lipopolysaccharides (LPS) is an important risk factor contributing to endothelial dysfunction.
Ming, Zhong, Xiong, Zhang, Xiaoming, Shi, Chao, Zheng   +3 more
openaire   +2 more sources

HUVEC replicative senescence

2016
Quantitative and integrated proteome and microRNA analysis of endothelial replicative ...
openaire   +1 more source

Suppression of HUVEC tissue factor synthesis by antisense oligodeoxynucleotide

Thrombosis Research, 2008
Tissue factor (TF) is an important regulator and effector molecule of coagulation. It is primary known as a cofactor for factor VIIa-mediated triggering of blood coagulation, which proceeds in a cascade of extracellular reactions, ultimately resulting in thrombin formation. In sepsis, expression of TF by activated monocytes, macrophages and endothelial
Alick C, Stephens, Nancy F, Ranlall, Rodney P A, Rivers   +2 more
openaire   +2 more sources

Fenofibrate activates AMPK and increases eNOS phosphorylation in HUVEC

Biochemical and Biophysical Research Communications, 2006
Fenofibrate improves endothelial function by lipid-lowering and anti-inflammatory effects. Additionally, fenofibrate has been demonstrated to upregulate endothelial nitric oxide synthase (eNOS). AMP-activated protein kinase (AMPK) has been reported to phosphorylate eNOS at Ser-1177 and stimulate vascular endothelium-derived nitric oxide (NO) production.
Hisashi, Murakami, Ryuichiro, Murakami, Fukushi, Kambe, Xia, Cao, Ryotaro, Takahashi, Toru, Asai, Toshihisa, Hirai, Yasushi, Numaguchi, Kenji, Okumura, Hisao, Seo, Toyoaki, Murohara   +10 more
openaire   +2 more sources

LPA2 and HUVEC

HUVEC cultured in room air or hyperoxia and treated with DMSO or LPA2 antagonist.
openaire   +1 more source

Suppression of Slit2/Robo1 mediated HUVEC migration by Robo4

Biochemical and Biophysical Research Communications, 2016
Slit proteins and their receptors, the Roundabout (Robo) family, are known to have a pivotal role in the vascular system. Slit2/Robo1 regulates the migration of human umbilical vein endothelial cells (HUVECs) and tumor-associated endothelial cells.
Satoshi, Enomoto, Kenichi, Mitsui, Takeshi, Kawamura, Hiroko, Iwanari, Kenji, Daigo, Keiko, Horiuchi, Takashi, Minami, Tatsuhiko, Kodama, Takao, Hamakubo   +8 more
openaire   +2 more sources

PKC delta knockdown in HUVECs

siRNA was used to knockdown PKC delta in HUVECs followed by RNA-seq .
openaire   +1 more source

HUVEC RNase L KD

HUVEC RNase L ...
openaire   +1 more source