Results 1 to 10 of about 3,533 (183)

Combined Effects of Pulmonary Hypertension and Heart Valve Calcification on Cardiovascular Outcomes in Maintenance Hemodialysis Patients: A Risk Stratification Study Using Echocardiography [PDF]

Kidney Diseases
Introduction: Cardiovascular disease remains the leading cause of mortality in maintenance hemodialysis (MHD) patients. While both pulmonary hypertension (PH) and heart valve calcification (HVC) are established independent risk factors for ...
Xinyi Fu, Chenyu Lei, Anning Xu, Linlin Yuan, Wenjing Cai, Li Zhang, Zhiming Ye, Xinling Liang, Min Wu, Zhilian Li   +9 more
doaj   +2 more sources

Cruzain Inhibitors for Chagas Disease: Anticorrelated Optimisation Landscapes and the Multiparametric Path to Clinical Candidates

Chemical Biology &Drug Design, Volume 107, Issue 6, June 2026.
Three decades of cruzain‐targeted drug discovery have yielded 215 sub‐micromolar inhibitors but no clinical candidates. This review diagnoses a systemic translational failure driven by single‐parameter optimisation and proposes a multiparametric framework integrating enzymatic potency, cathepsin selectivity, intracellular exposure, and metabolic ...
Caroline Rodrigues Chaves dos Reis, Hellen Valério Chaves Moura de Souza, Lidia Corrêa Parra, Guilber Valério Chaves Moura de Souza, Bruna Costa Zorzanelli, Nubia Boechat, Lucas Villas Bôas Hoelz, Tácio Vinício Amorim Fernandes   +7 more
wiley   +1 more source

Studies of HVC Plasticity in Adult Canaries Reveal Social Effects and Sex Differences as Well as Limitations of Multiple Markers Available to Assess Adult Neurogenesis.

PLoS ONE, 2017
In songbirds, neurogenesis in the song control nucleus HVC is sensitive to the hormonal and social environment but the dynamics of this process is difficult to assess with a single exogenous marker of new neurons. We simultaneously used three independent
Olesya T Shevchouk, Gregory F Ball, Charlotte A Cornil, Jacques Balthazart   +3 more
doaj   +1 more source

Constraints on the Space Density of Extragalactic HVCs

, 2000
High Velocity Clouds (HVCs) have recently attracted renewed attention as being long lived, massive dark matter dominated clouds of primordial composition distributed throughout the Local Group. In this picture the HVCs would contain a few times 10^7 M_sun of HI and would be at distances of a few hundred kpc to 1.5 Mpc from the Local Group barycenter ...
openaire   +3 more sources

Humanism at the Council of Constance. Diego de Anaya, Classical Manuscripts and Education in Salamanca

Renaissance Studies, Volume 40, Issue 3, Page 469-488, June 2026.
Abstract Due to their prolonged and multicultural nature, councils functioned historically as hubs for the exchange of ideas, discourse, diplomacy and rhetoric, reflecting broader cultural trends. In the Middle Ages, no international forums were comparable to ecumenical councils, where diverse and influential groups from various regions convened to ...
Federico Tavelli
wiley   +1 more source

Short‐Term Scheduling Optimization of a Single‐Pipeline Refining System With High Melting Point Crude Oil

Asia-Pacific Journal of Chemical Engineering, Volume 21, Issue 3, May/June 2026.
ABSTRACT In order to reflect the actual production situation more comprehensively and optimize the production cost, this paper solves the short‐term scheduling optimization problem for a single pipeline containing high melting point crude oil. Based on the refining plan given by the upper layer, a multi‐objective optimization model with high melting ...
Jing Yao, Xianxin Liu, Zhen Pan, Chengming Hao, Xiangwei Xu, Wei Jia   +5 more
wiley   +1 more source

Differential Surface Dynamics of LiCoO2 Through Solid Electrolyte Interface and Artificial Layer Under Varied Potential Conditions

EcoMat, Volume 8, Issue 5, May 2026.
At high voltage, structural phase transitions dominate degradation more than electrolyte side reactions. LiBOB has limited effectiveness in suppressing these high‐voltage phase transitions. However, under these high‐voltage conditions, Al2O3 coating, through process‐induced surface Al doping, effectively suppressed phase transitions and consequently ...
Meihua Hong, Feng Jiang, Van‐Chuong Ho, Hyojoo Lee, Hun‐Gi Jung, Junyoung Mun   +5 more
wiley   +1 more source

Caracterización de la evolución clínica del trasplante renal en pacientes con virus de la hepatitis C positivo

Revista Cubana de Medicina, 2020
RESUMEN Introducción: La infección por el virus de la hepatitis C es un evento común en los receptores de trasplante renal que la arrastran desde su estancia en los tratamientos de hemodiálisis previos al implante.
Gerardo Borroto Díaz
doaj  

The heart valve clinic at the heart hospital in Doha, Qatar: An evidence-based standard of care

Heart Views, 2018
The incidence of degenerative heart valve disease is rising in developing countries and diagnosis, assessment and management are becoming increasingly complex.
Alessandro Salustri, Salah El Badri, Abdul Haleem Shawky, Hakam Alzaeem   +3 more
doaj   +1 more source

The Nal Interstellar Spectrum of HVC 287.5 + 225 + 240 [PDF]

International Astronomical Union Colloquium, 1989
We present high resolution (FWHM≈7 km/sec) and high signal-to-noise observations of the bright Seyfert galaxy NGC3783 obtained with the CES spectrograph linked by fibres to the 3.6m telescope at La Silla, Chile.
openaire   +1 more source