Results 31 to 40 of about 30,672 (213)

Gingival Hypertrophy in a Child with Hyaline Fibromatosis Syndrome

Acta Stomatologica Croatica, 2020
Hyaline fibromatosis syndrome (HFS) is a rare autosomal recessive genetic disorder characterized by accumulation of hyalinized fibrous tissue with cutaneous, mucosal, osteoarticular, and systemic involvement.
Predrag Knežević, Marko Tarle, Lucija Ida Fratrić, Antonia Tarle, Hana Knežević-Krajina, Darko Macan   +5 more
doaj   +1 more source

Engineered Cyanobacteria‐Hydrogel Microecological System for Oxygen Reprogramming Synergizes Immunomodulation With Anabolism in Osteoarthritis Therapy

Advanced Science, EarlyView.
An injectable cyanobacteria‐laden hydrogel enables light‐dependent oxygen metabolism engineering for osteoarthritis therapy. Photosynthetic oxygen release under red light irradiation suppresses synovial inflammation via HIF‐1α inhibition and M2 macrophage polarization, while respiratory oxygen consumption in darkness stabilizes chondrocyte HIF‐1α to ...
Lerong Yang, Chong Shen, Hongjun Huang, Siyi Liu, Zeyu Huang, Licheng Xi, Huan Cao, Li Zheng, Zainen Qin   +8 more
wiley   +1 more source

Mitochondria‐Targeted Multimodal Nanotherapeutics Suppress Oxidized mtDNA‐Driven Inflammation at the Source

Advanced Science, EarlyView.
Ox‐mtDNA fragments escaping from mitochondria drive robust inflammatory responses. A targeted nanoplatform simultaneously inhibits mitochondrial FEN1‐mediated mtDNA cleavage and scavenges ROS, preventing the generation of immunogenic Ox‐mtDNA fragments. The released SeNPs further promote autophagic clearance of cytosolic mtDNA. Consequently, cGAS‐STING,
Wen‐Ling Li, Juan Cao, Yu‐Lin Wang, Yu‐Han Fan, Jia‐Qi Xu, Xian Wu Cheng, Lei Xing, Hu‐Lin Jiang   +7 more
wiley   +1 more source

Decoding the Glycan Signature of Hyalinized Pancreatic Carcinoma in Dogs: Histochemical and Lectin-Based Evidence of Extracellular Matrix Heterogeneity

Cluj Veterinary Journal
Hyalinizing pancreatic carcinoma in dogs is a rare tumor characterized by abundant eosinophilic extracellular material of uncertain composition. The aim of this study was to characterize the nature of hyaline deposits using histochemical and lectin ...
Ecaterina Semzenisi, Corina Toma, Haralambie Mara, Dragoș Hodor, Romelia Pop, Sorana Cătoi, Ibrahima Mamadou Sall, Alexia Teodora-Hoța, Alexandru Flaviu-Tăbaran   +8 more
doaj   +1 more source

Esophageal Aperistalsis in a Patient with Lipoid Proteinosis

Middle East Journal of Digestive Diseases, 2018
Lipoid proteinosis is a rare disorder with autosomal recessive inheritance, characterized by progressive deposition of hyaline material in the skin, mucous membrane, and different organs of the body, resulting in a multitude of clinical manifestations. A
Behrooz Afshar, Anahita Sadeghi, Mohammad Amani, Ali Ali Asgari   +3 more
doaj   +1 more source

A Dual‐Membrane Biomimetic Nanoplatform Enables Triple‐Modal Therapy Against SARS‐CoV‐2 Through Viral Decoy, Inflammation Neutralizing, and Intracellular RNAi

Advanced Science, EarlyView.
[A&T]MLN is a triple‐modal nanoplatform with siRNA‐loaded LN coated with hybrid ACE2/macrophage membrane. It blocks viral entry, neutralizes IL‐6/IL‐1β/TNF‐α, and delivers siRNA to suppress viral replication. In a murine lung injury model, it attenuates inflammation, offering a multi‐pronged strategy against SARS‐CoV‐2 variants and hyperinflammation ...
Hui Li, Bohan Zhang, Chao Shang, Yi Li, Te Zhao, Shengya Liu, Dan Liu, Junwei Che, Cuiling Zhang, Pinghui Wu, Wenjie Yang, Junjie Ding, Yuhua Ran, Yanan Zhai, Haihua Xiao, Jing Gao, Xiao Li, Chunsheng Gao, Lin Li, Zhiping Li   +19 more
wiley   +1 more source

Induced sepsis by cecal ligation and puncture in a rat model: hepatic and renal histological features

Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Veterinary Medicine, 2019
Animal models have been developed in an attempt to test potential therapeutic agents. The study aims to determine the hepatic and renal histological features induced by sepsis following cecal ligation and puncture (CLP) in a rat model.
Adrian Florin GAL, Sidonia BOGDAN, Flavia RUXANDA, Vasile RUS   +3 more
doaj   +1 more source

Fatal intestinal basidiobolomycosis in a pediatric patient

Journal of Pediatric Surgery Case Reports, 2022
Basidiobolomycosis is a rare but emerging fungal infection that causes severe and occasionally fatal illness. We present the case of a child with an abdominal mass and leukocytosis at the expense of eosinophilia, who underwent exploratory laparotomy ...
Pamela Fernandez, MD, Esperanza Vidales-Nieto, MD   +1 more
doaj   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

Advanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li   +7 more
wiley   +1 more source

Fundamentals, Advances, and Applications of Electrospun Nanofibrous 3D Materials

Journal of Applied Polymer Science, EarlyView.
Three‐dimensional electrospun nanofibrous systems offer unique properties and microenvironments. These properties are determined by the fabrication strategies employed and can be adjusted by the incorporation of functional additives to achieve multifunctionality for specific applications. The applications range from the biomedical to the environmental,
Rebecca Hengsbach, Viraj P. Nirwan, Altangerel Amarjargal, Zahra Asefi, Amir Fahmi   +4 more
wiley   +1 more source