Wrapping of Microparticles by Floppy Lipid Vesicles [PDF]
Lipid membranes, the barrier defining living cells and many of their sub-compartments, bind to a wide variety of nano- and micro-meter sized objects. In the presence of strong adhesive forces, membranes can strongly deform and wrap the particles, an essential step in crossing the membrane for a variety of health and disease-related processes.
arxiv +1 more source
TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics. [PDF]
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are age-related neurodegenerative disorders with shared genetic etiologies and overlapping clinical and pathological features. Here we studied a novel ALS/FTD family and identified the
Annu, Kavya+41 more
core +2 more sources
The Human Plasma Membrane Peripherome: Visualization and Analysis of Interactions [PDF]
A major part of membrane function is conducted by proteins, both integral and peripheral. Peripheral membrane proteins temporarily adhere to biological membranes, either to the lipid bilayer or to integral membrane proteins with non-covalent interactions.
arxiv +1 more source
Ewing and Ewing‐like sarcomas: A morphological guide through genetically‐defined entities
Abstract The fifth edition of the World Health Organization classification of soft tissue and bone tumors redefined Ewing sarcoma by fusions between EWSR1/FUS and ETS family of transcription factors, and recognized three tumor groups among Ewing‐like sarcoma: CIC‐rearranged sarcoma, sarcoma with BCOR genetic alterations, and round cell sarcoma with ...
Akihiko Yoshida
wiley +1 more source
Context: Neonatal period is the single most hazardous period of life. The major causes of neonatal death are prematurity and respiratory distress syndrome. We report a series of neonatal autopsies in our Neonatal Intensive Care Unit with special emphasis
Indranil Das+5 more
doaj +1 more source
Clinical biological and genetic heterogeneity of the inborn errors of pulmonary surfactant metabolism [PDF]
Pulmonary surfactant is a multimolecular complex located at the air-water interface within the alveolus to which a range of physical (surface-active properties) and immune functions has been assigned. This complex consists of a surface-active lipid layer
Clements JA+29 more
core +1 more source
Neonatal acute liver failure with pulmonary yellow hyaline membrane and kernicterus [PDF]
Background: Neonatal acute liver failure (NALF) is a rare and life-threatening condition. It causes bilirubin to accumulate to a dangerous level in the body, causing permanent damage to vital organs such as the brain and lungs.
Brathwaite, Carole+4 more
core +3 more sources
Respiratory Distress in Full Term Outborn Neonates: A Hospital Based Study
Summary: Background: Respiratory distress remains a major problem post adaptation and one of the most common reasons for admission of neonates to Intensive Care. Objectives: To study the causes and short term outcomes of respiratory distress in full term
Manal B. Naoom+2 more
doaj +1 more source
The respiratory distress syndrome of the newborn : studies of blood gases and acid/base balance with the object of formulating principles of treatment [PDF]
Respiratory failure accounts for a large, if not the largest, percentage of deaths during the first 48 hours of life. During the last ten years a great deal of research has been devoted to this early respiratory failure.
Warley, Mogamat Arashat
core +1 more source
Localization and potential role of matrix metalloproteinase-1 and tissue inhibitors of metalloproteinase-1 and -2 in different phases of bronchopulmonary dysplasia [PDF]
Bronchopulmonary dysplasia (BPD) can evolve in prematurely born infants who require mechanical ventilation because of hyaline membrane disease (HMD).
Adamson IY+49 more
core +5 more sources