Results 31 to 40 of about 23,436 (153)

Pathophysiological and Molecular Features of DXd ADC‐Related Interstitial Pneumonitis in Cynomolgus Monkeys

open access: yesCancer Science, EarlyView.
An interstitial lung disease model for DXd antibody‐drug conjugates was established in cynomolgus monkeys by weekly dosing of a non‐targeting DXd ADC. Integrated analysis of bronchoalveolar lavage fluid–derived extracellular vesicle proteomics and lung single‐cell RNA sequencing reveals cell‐type‐resolved molecular features of DXd ADC‐related lung ...
Kazuyoshi Kumagai   +5 more
wiley   +1 more source

Light‐Inducible Activation of FGFR3 Facilitates Chondrocyte Maturation

open access: yesCell Proliferation, EarlyView.
Light‐inducible activation of FGFR3 induced robust activation of MAPK signaling, promoting proliferation and collagen depositon in induced chondrocytes and prevent the degeneration of osteoarthritic chondrocytes.
Mengze Sun   +5 more
wiley   +1 more source

Laboratory Biology, Immature and Adult Morphology of Trichopria drosophilae (Perkins) (Hymenoptera: Diapriidae), Parasitoids of Drosophila Flies

open access: yesEntomologia Experimentalis et Applicata, EarlyView.
This study investigates the laboratory biology and morphology of the parasitoid Trichopria drosophilae, which targets Drosophila flies, including the invasive Drosophila suzukii. Key findings include a detailed description of the parasitoid's egg, three larval instars, and pupal stage, as well as unique behaviors such as siblicide and encapsulation in ...
Alex Gumovsky   +3 more
wiley   +1 more source

Proteolytic remodelling of the extracellular matrix by pericytes

open access: yesThe FEBS Journal, EarlyView.
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard   +4 more
wiley   +1 more source

Epithelial-Myoepithelial Carcinoma of Minor Salivary Glands of the Palate: A Systematic Review. [PDF]

open access: yesHealth Sci Rep
ABSTRACT Background and Aims Epithelial‐myoepithelial carcinoma (EMC) is a very rare malignant neoplasm of the salivary glands. It mainly affects the major salivary glands. Little is known about the specificity of EMC in minor salivary glands (MSGs), which represents a diagnostic challenge. Methods A systematic review was performed to identify clinical
Khattab NM, Seveyrat R, Taihi I.
europepmc   +2 more sources

The 2025 ATS/ERS update of the international multidisciplinary classification of the interstitial pneumonias: implications for the pathologist

open access: yesHistopathology, EarlyView.
This review highlights changes relevant to pathologists in the updated multidisciplinary classification of interstitial pneumonias. Changes include expansion beyond idiopathic disease, subclassification as interstitial (fibrotic vs non‐fibrotic) and alveolar filling disorders, expansion to include additional patterns (e.g.
Andrew G Nicholson   +7 more
wiley   +1 more source

Timing of Delivery in Preeclampsia: Time to Reconsider?

open access: yes
BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
Rebecca Horgan   +5 more
wiley   +1 more source

Anti‐Proliferative Effects of Resveratrol on Gingival Fibroblasts Derived From Amlodipine‐Induced Gingival Overgrowth

open access: yesJournal of Periodontal Research, EarlyView.
Resveratrol in repeated doses has been shown to suppress excessive cell proliferation without cytotoxic effects in amlodipine‐induced gingival hyperplasia, while not having a negative effect on mediators involved in tissue homeostasis in healthy cells, and at the same time, it reduces the expression of biomarkers involved in fibrosis processes ...
Bilkan Kara   +6 more
wiley   +1 more source

Mast Cells in Acute COVID‐19 Patients

open access: yes
Allergy, EarlyView.
Ilan Zaffran   +8 more
wiley   +1 more source

Hyaluronic acid: A novel approach in regenerative/reconstructive periodontal therapy?

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Although hyaluronic acid (HA) has long been used for many medical applications, only in recent years has it gained greater popularity in the field of periodontics because of its biological effects during wound healing. Even today, most clinicians are not aware that more than one type of HA exists and that the extent of its ...
Andrea Pilloni   +7 more
wiley   +1 more source

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