Results 71 to 80 of about 40,589 (263)

Histochemical Analysis of Paraspinal Rotator Muscles From Patients With Adolescent Idiopathic Scoliosis A Cross-Sectional Study [PDF]

, 2015
Morphological, biochemical, and histopathological alterations in the paraspinal skeletal muscle of patients with adolescent idiopathic scoliosis (AIS) have been extensively reported.
Del Curto, David, Faloppa, Flavio, Luciano, Rafael de Paiva, Martins, Delio Eulalio, Oliveira, Acary Souza Bulle, Puertas, Eduardo Barros, Schmidt, Beny, Wajchenberg, Marcelo   +7 more
core   +2 more sources

Expansion of the Phenotypic and Genotypic Spectrum for PRKAR1B‐Related Marbach–Schaaf Neurodevelopmental Syndrome: A Case Series

Clinical Genetics, EarlyView.
Comprehensive clinical description of 12 subjects with pathogenic PRKAR1B variants, including two heterozygous deletions supporting haploinsufficiency as a possible mechanism of disease, providing valuable insight into the pathophysiology of MASNS and setting a framework upon which to design future mechanistic studies of PKA signaling in brain ...
Sebastian Burkart, Tarik Guzeloglu, Ana R. Soares, Irene Valenzuela, Eduardo F. Tizzano, David Gómez‐Andres, Laurent Pasquier, Marine Legendre, Camille Berges, Julien Thevenon, Marjolaine Gauthier, Caleb Heid, Elly Ranum, Joseph Shen, Michelle Frees, Michael W. Schmidtke, Caro Pilar, Christian P. Schaaf   +17 more
wiley   +1 more source

Mechanism of ITGB2 in Osteoclast Differentiation in Osteoarthritis

Cell Proliferation, EarlyView.
In osteoclast precursors, higher ITGB1 than ITGB2 expression increases ITGA2‐ITGB1 integrin. In OA, extracellular signals upregulate ITGB2 and downregulate ITGB1, enhancing ITGA2‐ITGB2 integrin. This activates Rac1 to Rac‐GTP, driving osteoclast differentiation. Hyperactive subchondral osteoclasts accelerate OA progression.
Yang Yang, Rui Sun, Zhibin Lan, Qi Ma, Gang Wu, Di Xue, Zhirong Chen, Yajing Su, Ye Ma, Xiaolei Chen, Jiangbo Yan, Long Ma, Xiaoxin He, Kuanmin Tian, Xiaoyi Ma, Xue Lin, Qunhua Jin   +16 more
wiley   +1 more source

Lobar Emphysema Successfully Operated in an Extreme Premature Neonate

Indian Pediatrics Case Reports
Background: Lobar emphysema in a newborn may be due to a rare congenital developmental anomaly of the lung, termed congenital lobar emphysema (CLE) or may develop secondary to lung damage, especially with positive airway pressures in premature newborns ...
Mario Joseph Bukelo, Shreya Adavalath, Sadashiva Rao   +2 more
doaj   +1 more source

Clinical and molecular study of the extracellular matrix protein 1 gene in a spanish family with lipoid proteinosis [PDF]

, 2017
[Background] Lipoid proteinosis (LP) is a rare autosomal recessive disorder characterized by a hoarse voice, variable scarring, and infiltration of the skin and mucosa.
Delgado-Valverde, Mercedes, García-Bravo, Begoña, García-Moreno, José Manuel, Lucas, Miguel, Martínez Mir, Amalia, Mondéjar, Rufino, Rubio, Rocío, Ríos-Martín, Juan José, Solano, Francisca   +8 more
core   +1 more source

A retrospective case series of 66 foals with presumed acute interstitial pneumonia

Equine Veterinary Education, EarlyView.
Summary Background There is limited literature describing acute interstitial pneumonia (AIP) in foals. Objectives Description of clinical and ultrasonographic findings in 66 foals affected by AIP. Investigation into whether the number of AIP cases is associated with specific climatic conditions. We also investigated whether clinical, haematological and
L. Weißlein, F. Freise, M. Venner
wiley   +1 more source

Role of artificial intelligence in earlier diagnosis of bronchopulmonary dysplasia

Journal of Pediatric and Neonatal Individualized Medicine
Bronchopulmonary dysplasia (BPD) affects premature infants and causes long-term breathing problems. Along with respiratory complications, BPD can also lead to developmental delays, poor growth, pulmonary hypertension, heart failure, and hearing ...
Lam Q. Bui, Sandhya J. Kadam
doaj   +1 more source

Mesenchymal stem cells as a potential therapy for COVID-19

Stem Cell Research & Therapy, 2020
The outbreak of 2019 novel coronavirus disease (COVID-19) worldwide is becoming rapidly a major concern. The number of severe cases has increased dramatically worldwide, while specific treatment options are scarce.
Shan Liu, Danyi Peng, Huijun Qiu, Ke Yang, Zhou Fu, Lin Zou   +5 more
doaj   +1 more source

Equine experimental lameness induction models

Equine Veterinary Education, EarlyView.
Summary Equine lameness due to musculoskeletal injury remains a common and significant cause of decreased performance. While our understanding and management of lameness have improved with advanced imaging, as well as diagnostic and therapeutic progression, a need for experimental equine models of lameness remains.
A. Dockery, B. Beasley, V. J. Moorman
wiley   +1 more source

Myocardial infarction and subsequent pregnancy

Arquivos Brasileiros de Cardiologia, 2000
We report the case of a 40-year-old woman with 2 previous myocardial infarctions, revascularization surgery, and an ongoing pregnancy complicated with preeclampsia and fetal hypoxia.
Tedoldi Citânia Lúcia, Manfroi Waldomiro Carlos   +1 more
doaj