Results 71 to 80 of about 37,050 (279)

PRMT5:MEP50 Are Mediators of Treatment‐Induced Neuroendocrine Differentiation in Prostate Cancer

The Prostate, EarlyView.
ABSTRACT Background Neuroendocrine prostate cancer (NEPC) is a lethal subtype of prostate cancer responsible for an estimated 20%–30% of castration‐resistant prostate cancer (CRPC) deaths. While NEPC can arise spontaneously, the majority of these cases emerge as treatment‐induced NEPC (tNEPC).
Hye Seung Nam, Andrew Michael Asberry, Xuehong Deng, Sheng Liu, Jiaoti Huang, Chang‐Deng Hu, Jun Wan, Michael K. Wendt   +7 more
wiley   +1 more source

Role of artificial intelligence in earlier diagnosis of bronchopulmonary dysplasia

Journal of Pediatric and Neonatal Individualized Medicine
Bronchopulmonary dysplasia (BPD) affects premature infants and causes long-term breathing problems. Along with respiratory complications, BPD can also lead to developmental delays, poor growth, pulmonary hypertension, heart failure, and hearing ...
Lam Q. Bui, Sandhya J. Kadam
doaj   +1 more source

Mesenchymal stem cells as a potential therapy for COVID-19

Stem Cell Research & Therapy, 2020
The outbreak of 2019 novel coronavirus disease (COVID-19) worldwide is becoming rapidly a major concern. The number of severe cases has increased dramatically worldwide, while specific treatment options are scarce.
Shan Liu, Danyi Peng, Huijun Qiu, Ke Yang, Zhou Fu, Lin Zou   +5 more
doaj   +1 more source

Diagnostic Ability of Transverse Axial Images Obtained by Optical Coherence Tomography for Detecting Anterior Displacement of Peripapillary Tissues in Papilledema

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To evaluate the diagnostic ability of optical coherence tomography (OCT) images to detect posterior pole deformation and anterior displacement of the optic disc (ADOD) in papilledema before and after intracranial pressure reduction with medical treatment.
Gabriel Castilho S. Barbosa, Rodrigo S. Pegado, Fernanda N. Susanna, Kenzo Hokazono, Mário Luiz R. Monteiro, Leonardo Provetti Cunha   +5 more
wiley   +1 more source

Lobar Emphysema Successfully Operated in an Extreme Premature Neonate

Indian Pediatrics Case Reports
Background: Lobar emphysema in a newborn may be due to a rare congenital developmental anomaly of the lung, termed congenital lobar emphysema (CLE) or may develop secondary to lung damage, especially with positive airway pressures in premature newborns ...
Mario Joseph Bukelo, Shreya Adavalath, Sadashiva Rao   +2 more
doaj   +1 more source

Mechanism of ITGB2 in Osteoclast Differentiation in Osteoarthritis

Cell Proliferation, EarlyView.
In osteoclast precursors, higher ITGB1 than ITGB2 expression increases ITGA2‐ITGB1 integrin. In OA, extracellular signals upregulate ITGB2 and downregulate ITGB1, enhancing ITGA2‐ITGB2 integrin. This activates Rac1 to Rac‐GTP, driving osteoclast differentiation. Hyperactive subchondral osteoclasts accelerate OA progression.
Yang Yang, Rui Sun, Zhibin Lan, Qi Ma, Gang Wu, Di Xue, Zhirong Chen, Yajing Su, Ye Ma, Xiaolei Chen, Jiangbo Yan, Long Ma, Xiaoxin He, Kuanmin Tian, Xiaoyi Ma, Xue Lin, Qunhua Jin   +16 more
wiley   +1 more source

Endotracheal instillation of prostacyclin in preterm infants with persistent pulmonary hypertension [PDF]

, 1998
Does endotracheal instilled prostacyclin (epoprostenol) improve oxygenation in preterm infants with persistent pulmonary hypertension? Four preterm infants were studied.
Anker, J.N. (John) van den, Jaegere, A. (Anne) de   +1 more
core   +1 more source

The Prognostic Significance of Tumoral Melanosis

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Tumoral melanosis (TM) is a histological term to describe a nodular aggregation of macrophages containing melanin pigment (melanophages) that is devoid of viable melanocytes. It is most often identified in skin, where it may be appreciated clinically as a pigmented lesion; however, it can also be found in other organs such as lymph ...
Alison J. Potter, Peter M. Ferguson, Serigne N. Lo, Tasnia Ahmed, Robert V. Rawson, John F. Thompson, Georgina V. Long, Richard A. Scolyer   +7 more
wiley   +1 more source

Myocardial infarction and subsequent pregnancy

Arquivos Brasileiros de Cardiologia, 2000
We report the case of a 40-year-old woman with 2 previous myocardial infarctions, revascularization surgery, and an ongoing pregnancy complicated with preeclampsia and fetal hypoxia.
Tedoldi Citânia Lúcia, Manfroi Waldomiro Carlos   +1 more
doaj  

Osteochondrosis in horses: An overview of genetic and other factors

Equine Veterinary Journal, EarlyView.
Abstract Osteochondrosis (OC) is a frequent manifestation of developmental orthopaedic disease, and its severe clinical presentation is known as OC dissecans (OCD). OC is defined as a disruption of the endochondral ossification process in the epiphyseal cartilage, and this disease has been reported in different mammalian species, including humans, dogs,
Lola Martinez‐Saez, Pablo J. Marín‐García, M. Lola Llobat   +2 more
wiley   +1 more source