Results 91 to 100 of about 108,598 (297)

A Systematic Study of GelMA‐Carbopol Bioinks for High‐Fidelity Extrusion 3D Bioprinting at Physiological Temperatures

Advanced Healthcare Materials, EarlyView.
Gonzalez Martinez and collaborators develop a strategy to formulate high performance GelMA‐based bioinks with low solids contents. The resulting bioinks enable 3D bioprinting at 37 °C of high‐fidelity structures with tunable mechanical properties that support high cell viability and function.
David A. González‐Martínez, Aidee V. Arizpe Tafoya, Eduardo González‐Martínez, Mabel Barreiro Carpio, Laura Daniela Serrano Andrade, Christopher T. N. Chow, Mohammadhossein Dabaghi, Jeremy A. Hirota, Jose M. Moran‐Mirabal   +8 more
wiley   +1 more source

Self‐Assembled Skin Equivalents with Monoclonal CRISPR/Cas9‐Modified N/TERT‐1 Keratinocytes: A Cutting‐Edge model for Human Skin and its Diseases

Advanced Healthcare Materials, EarlyView.
Self‐assembled, scaffold‐free full‐thickness skin equivalents with monoclonal, genetically modified N/TERT‐1 keratinocytes represent a novel in vitro model of human skin and skin diseases. The model is highly robust, reproducible, physiologically relevant, and suitable for high‐throughput applications.
Marta Slaufova, Tugay Karakaya, Michela Di Filippo, Thomas Kündig, Hans‐Dietmar Beer   +4 more
wiley   +1 more source

Spectral manifestations of hyaluronic acid intermolecular interaction with nitrogen-containing amino acids [PDF]

Известия Саратовского университета. Новая серия: Физика
Background and Objectives: Manifestations of intermolecular interaction based on hydrogen bonding in hyaluronic acid IR spectra and in multicomponent mixtures of hyaluronic acid with nitrogen-containing amino acids, which are part of mucin of the mucous ...
Plastun, Inna L'vovna, Bryksin, Kirill A., Mayorova, Oksana Aleksandrovna, Babkov, Lev Mikhailovich   +3 more
doaj   +1 more source

Emergence of a new highly successful acapsular Group A Streptococcus clade of the genotype emm89 in the United Kingdom [PDF]

, 2015
This work was supported by the National Institute for Health Research Biomedical Research Centre awarded to Imperial College Healthcare Trust, and the UK Clinical Research Collaboration (National Centre for Infection Prevention & Management).Group A ...
Abbott, James, Holden, M.T., Holden, MTG, Sriskandan, S., David, Sophia, Jones, Michael D., Lamagni, T., Game, L, Sophia David, Turner, C.E., Sriskandan, S, Shiranee Sriskandan, David, S, Efstratiou, A, Michael D. Jones, Androulla Efstratiou, Efstratiou, A., David, S., Laurence Game, Game, Laurence, Matthew T. G. Holden, Turner, CE, Jones, M.D., Abbott, J., Abbott, J, Claire E. Turner, Efstratiou, Androulla, Theresa Lamagni, Lamagni, Theresa, Holden, Matthew, Jones, MD, James Abbott, Game, L., Turner, Claire E., Sriskandan, Shiranee, Lamagni, T   +35 more
core   +1 more source

A Versatile Microfluidic Extrusion‐Based Hydrogel Platform for Self‐Organization and Long‐Term Maintenance of Engineered 3D Lymphatic Endothelium

Advanced Healthcare Materials, EarlyView.
Microfluidic coaxial extrusion generates size‐controlled 3D lymphatic tubes from primary human dermal lymphatic endothelial cells in a defined four‐component matrix. These engineered vessels self‐organize into stable lymphatic endothelium, maintain selective macromolecular permeability for 30 days, and enable direct comparison with blood endothelial ...
Elsa Mazari‐Arrighi, Adeline Boyreau, Laura Chaillot, Wilfried Souleyreau, Laetitia Andrique, Pierre‐Olivier Guichet, Thomas Mathivet, Andreas Bikfalvi, Pierre Nassoy   +8 more
wiley   +1 more source

Standardized Effect Measures Informing Next‐Generation Strategies for Mechanical Stimulation in Cartilage Tissue Engineering

Advanced Healthcare Materials, EarlyView.
This systematic review quantitatively compares conventional mechanical stimulation strategies in cartilage tissue engineering across 85 heterogeneous in vitro studies. Applying standardized effect measures, meta‐analysis reveals that combined compression and shear loading optimally promotes cartilage matrix development.
Jiaqi K. Shen, Tony B. Huang, Catherine E. Davey, Elias Salzer, Gerjo J. V. M. Van Osch, Sandra J. Shefelbine, Marcus G. Pandy, Kathryn S. Stok   +7 more
wiley   +1 more source

Microgel‐Based 3D Bioprinting: A Convergent Strategy Integrating Material Design, Jamming Dynamics, and Biological Function

Advanced Healthcare Materials, EarlyView.
Microgel‐based 3D printed constructs represent a compelling and versatile innovation for engineering architecturally complex, dynamically remodelable, and biocompatible structures with high structural fidelity and bioactivity. By integrating material design, biofabrication, and biological function, these systems enable the development of adaptive ...
Elena Ghighină, Andreea Ioana Dinu, Jana Ghițman   +2 more
wiley   +1 more source

Physicochemical analysis of hyaluronic acid powder for cosmetic and pharmaceutical processing

, 2016
Hyaluronic acid (HA) is found in extracellular tissue in many parts of the body. It is a material of increasing importance to biomaterials science and is finding applications in diverse areas ranging from tissue culture scaffolds to cosmetic materials ...
Lapčík, Lubomír, Vlček, Jakub, Otyepková, Eva, Otyepka, Michal, Kupská, Ivana, Lapčíková, Barbora   +5 more
core  

Adaptable Covalent Organic Framework‐Hydrogel Microneedles for Glucose‐Responsive Isoliquiritigenin Delivery in Diabetic Wound Therapy

Advanced Healthcare Materials, EarlyView.
We develop a covalent organic framework‐loaded Traditional Chinese Medicine monomer nanodrug delivery system (ISL@bCOF) via boron‐oxygen bonds, a smart response to glucose for delivering AI‐driven isoliquiritigenin (ISL) targeting ZBP1. This dynamic release mechanism, combined with transdermal delivery technology via potent microneedles, can modulate ...
Menghan Zhou, Zongjie Hu, Xiuwen Li, Huaman Geng, Yang Liu, Yajie Wang, Yunshu Yang, Guangdong Zhou, Yujie Hua, Di Wang   +9 more
wiley   +1 more source

Meta-analysis on the use of hyaluronic acid gel to prevent recurrence of intrauterine adhesion after hysteroscopic adhesiolysis

Taiwanese Journal of Obstetrics & Gynecology, 2019
Intrauterine adhesion is a severe complication after intrauterine operation, Various adjuvant therapies failed to improve clinical symptoms and pregnancy rates among patients with moderate-to-severe intrauterine adhesion.
Zheng Fei, Zhu Bin, Xin Xin, He Fei, Cui Yuechong   +4 more
doaj   +1 more source