Results 191 to 200 of about 109,214 (299)

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

open access: yesBMEMat, EarlyView.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang   +13 more
wiley   +1 more source

Dual‐targeted nanomedicine delivering doxorubicin and nitric oxide for tumor immunomodulation and synergistic therapy

open access: yesBMEMat, EarlyView.
The mechanism of HA‐DS@PLGA nanoparticles co‐delivering DOX and SNAP (an NO donor) to suppress tumor growth, remodel the tumor microenvironment, and enhance antitumor immune responses for effective combinatorial cancer therapy. Abstract Cancer therapeutic efficacy is significantly influenced by tumor immunosuppressive environment possibly induced by ...
Xingzhou Peng   +10 more
wiley   +1 more source

Covalent grafting of hyaluronic acid on drug nanocrystals for mucosal delivery.

open access: yesJ Mater Chem B
Fuster MG   +4 more
europepmc   +1 more source

Crosslinking-Dependent Design of Hyaluronic Acid Matrices for Enhanced Bioadhesion and Cellular Response. [PDF]

open access: yesPharmaceutics
Panainte AD   +11 more
europepmc   +1 more source

Orchestrating the metastatic symphony: the role of extracellular vesicles in the epithelial–mesenchymal transition and pulmonary niche formation of breast cancer

open access: yesBiological Reviews, EarlyView.
ABSTRACT The complexity of breast cancer (BC) lung metastasis lies in the capacity of tumour cells to interact efficiently with distant organs to promote colonisation, a process that involves the sophisticated coordination of inherent cellular plasticity and the remodelling of the distant microenvironment.
Jian Lu   +12 more
wiley   +1 more source

Oocyte–cumulus cell interaction: a key factor in early embryo development

open access: yesBiological Reviews, EarlyView.
ABSTRACT The evaluation of oocyte competence is a fundamental step in achieving successful outcomes following assisted reproduction techniques (ART). At present, however, conventional oocyte maturation assessment is carried out by morphological observation, which is a subjective method that does not consider molecular features.
Marc Torres‐Garrido   +2 more
wiley   +1 more source

Temporal Filling and Facial Lifting: Rethinking Expectations

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Temporal lifting using injectable fillers has gained considerable attention in facial esthetics, based on the anatomical principle that strategic volumization can produce lifting effects through mechanical transmission of forces. However, there is a significant gap between anatomical plausibility and clinical evidence.
Marcelo Germani
wiley   +1 more source

Hyaluronic acid degradation by Purpureocillium lilacinum: biochemical and transcriptomic insights. [PDF]

open access: yesAppl Microbiol Biotechnol
Minguet-Lobato M   +4 more
europepmc   +1 more source

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