Results 111 to 120 of about 45,530 (278)

Purification of human serum hyaluronidase using chromatofocusing

, 1982
Udgivelsesdato: 1982-May-7A commercial chromatofocusing system was applied to Cohn's fraction III of human serum to purify hyaluronidase (E.C.3.2.1.3.5).
Fenger, M
core   +1 more source

Aspirin augments hyaluronidase induced adhesion inhibition

, 2004
Postoperative adhesions occur after virtually all abdomino-pelvic surgery and are the leading cause of intestinal obstruction and other gynaecologic problems.
AA Oremosu, Okanlawon, AA, Oremosu, AA, FI Duru, Duru, FI, AA Okanlawon   +5 more
core   +1 more source

Regulatory harmonization: Evolution, globalization and future directions

British Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm, Elaine Y. L. Blair, Christine Y. Lu   +2 more
wiley   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Efficacy of oral colchicine and intralesional hyaluronidase with and without ultrasound therapy in the management of oral submucous fibrosis—A comparative study

Journal of Pharmacy and Bioallied Sciences
Aim: To determine the therapeutic effect and efficacy of oral colchicine tablet and intralesional injection of hyaluronidase with and without ultrasound therapy in the clinical course of oral submucous fibrosis.
Malabika Shil, Poulami Goswami, Trupti Vijay Gaikwad, Gargi Jadaun, T Sridhar, Basudhara Bandyopadhyay, Pratik Surana   +6 more
doaj   +1 more source

Hyaluronidase Iontophoresis [PDF]

Physical Therapy, 1969
openaire   +2 more sources

Model‐based clinical pharmacology profiling of subcutaneous nivolumab in renal cell carcinoma: Bridging to alternative dosing regimens and indications

Clinical Pharmacology &Therapeutics, EarlyView.
A novel model‐informed drug development (MIDD) approach was employed to derive the coprimary endpoints (time‐averaged serum concentration over 28 days [Cavgd28] and minimum serum concentration at steady state [Cminss]) of the phase III CheckMate 67T study (NCT04810078).
Yue Zhao, Zheyi Hu, Elizabeth Gibson, Li Zhu, Heather Vezina, Anna G. Kondic   +5 more
wiley   +1 more source

HYALURONIDASE ACTIVITY OF ALVEOLAR MACROPHAGES

, 1968
Hyaluronidase activity was detected in preparations of isolated rabbit lung alveolar macrophages. The enzyme manifested a pH optimum of 3.9 with no activity detected above pH 5.
GERALD S. LAZARUS, JOHN F. GOGGINS, HAROLD M. FULLMER   +2 more
core   +1 more source

Dosimetry, Toxicity and Stability Associated With a Hyaluronic Acid‐Based Prostate‐Rectal Spacing Device During Prostate Radiation Therapy: A Retrospective Comparative Analysis

Journal of Medical Radiation Sciences, EarlyView.
Rectal spacers composed of stabilised hyaluronic acid facilitated a favourable toxicity profile compared to no spacing during prostate radiation therapy. Acute GI toxicity (grade ≥ 1) was lower in the spacer cohort (23.5% vs. 48.0%; odds ratio = 0.33, p = 0.05) with grade ≥ 2 toxicity substantially lower (2.9% vs. 20.0%).
Fadila Najem, Bridget Smith, Sary Chen, Lucinda Wood, Asmaa El‐Heneidy, Lloyd Smyth, Hodo Haxhimolla, Pat Bowden   +7 more
wiley   +1 more source

Comparison of the effects of submucosal hyaluronidase and dexamethasone on postoperative edema, pain, trismus, and infection following impacted third molar surgery

BMC Oral Health
Background Limiting postoperative edema, pain, trismus, and infection is crucial for smooth healing. This prospective, controlled clinical trial investigated and compared the effectiveness of dexamethasone and hyaluronidase in relieving these ...
Onur Koç, Nuray Er, Çiğdem Karaca, Kanİ Bilginaylar   +3 more
doaj   +1 more source