Results 191 to 200 of about 45,530 (278)

Elamipretide Rejuvenates Oocyte Quality and Restores Female Fertility During Reproductive Aging

open access: yesAging Cell, Volume 25, Issue 10, October 2026.
We reported a novel peptide therapy showing that elamipretide restores the quality of aged oocytes for fertility by coordinately boosting oocyte nuclear and cytoplasmic maturation via activation of the VEGF signaling pathway. ABSTRACT Aging represents a major contributor to the deterioration of female fertility, with oocyte quality being the central ...
Hao‐Lin Zhang   +12 more
wiley   +1 more source

FDX1 Depletion Activates CD8+ T Cell Antitumor Immunity by Promoting DMBT1 Secretion in Cuproptosis of Colorectal Cancer

open access: yesCancer Science, Volume 117, Issue 10, Page 2659-2675, October 2026.
Elesclomol‐induced cuproptosis potently activates both innate and adaptive antitumor immunity, especially CD8+ T cell immunity. FDX1 serves as a central regulator of CD8+ T cell functionality through DMBT1 downregulation during cuproptosis in colorectal cancer.
Jieqiong Wu   +22 more
wiley   +1 more source

A Composite Ovine Forestomach Matrix and Hyaluronic Acid CAMP for the Treatment of Full Thickness Wounds of the Foot in People With Diabetes: A Randomized Controlled Trial

open access: yesInternational Wound Journal, Volume 23, Issue 10, October 2026.
ABSTRACT Diabetic foot ulcers (DFUs) are a devastating complication of diabetes that markedly affects quality of life and generates significant socioeconomic and healthcare burdens. When DFUs fail to respond to standard of care (SOC), advanced therapies including Cellular, Acellular and Matrix‐like Products (CAMPs) are often employed. A novel composite
David G. Armstrong   +9 more
wiley   +1 more source

Target Treatment Zones: A Zone‐Based Clinical Framework for Skin Quality Improvement Using Non–Cross‐Linked Hyaluronic Acid and Glycerol

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 10, October 2026.
ABSTRACT Background Aesthetic medicine has progressively shifted from volume toward skin quality as a key determinant of perceived age and facial attractiveness. Although non–cross‐linked hyaluronic acid–based injectables are widely used to improve skin hydration and appearance, clinical application remains largely technique‐driven, and structured ...
Vorapot Siramangkhalanon   +2 more
wiley   +1 more source

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