Results 221 to 230 of about 45,530 (278)
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A Microplate Assay for Hyaluronidase and Hyaluronidase Inhibitors
Analytical Biochemistry, 1994A sensitive, high-throughput assay has been developed which measures hyaluronidase activity in a microplate format. In this assay, hyaluronic acid is suspended in agarose in a microtiter well, the plate is incubated with the hyaluronidase solution, and the undigested hyaluronic acid is precipitated with cetylpyridinium chloride.
J S, Tung, G E, Mark, G F, Hollis
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Journal of Neurochemistry, 1972
Abstract— Hyaluronidase (hyaluronate glycanohydrolase, EC 3.2.1.35), with a pH optimum of 3.7, was detected in rat and bovine brain. It degraded hyaluronic acid and, at a slower rate, chondroitin sulphate to a mixture of higher oligosaccharides with N‐acetylhexosamine at the reducing end.
R U, Margolis +3 more
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Abstract— Hyaluronidase (hyaluronate glycanohydrolase, EC 3.2.1.35), with a pH optimum of 3.7, was detected in rat and bovine brain. It degraded hyaluronic acid and, at a slower rate, chondroitin sulphate to a mixture of higher oligosaccharides with N‐acetylhexosamine at the reducing end.
R U, Margolis +3 more
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Journal of the American Medical Association, 1948
The enzyme hyaluronidase has been implicated in the process of fertility primarily as the result of the following reports. McClean and Rowlands1and Fekete and Duran-Reynals2showed that the ovum in the fallopian tubes is covered with many follicular cells which are embedded in a thick, viscous gell-like material. Before the sperm can penetrate the ovum,
D M, BERGENSTAL, W W, SCOTT
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The enzyme hyaluronidase has been implicated in the process of fertility primarily as the result of the following reports. McClean and Rowlands1and Fekete and Duran-Reynals2showed that the ovum in the fallopian tubes is covered with many follicular cells which are embedded in a thick, viscous gell-like material. Before the sperm can penetrate the ovum,
D M, BERGENSTAL, W W, SCOTT
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Archives of Otolaryngology - Head and Neck Surgery, 1950
DURING the last few years there has been a widespread increase in the clinical use of hyaluronidase, the specific enzyme now generally conceded to be the "spreading factor" of Duran-Reynals 1 and McClean. 2 Various authors have reported its effectiveness in facilitating the absorption of fluids by hypodermoclysis 3 and in effecting better local ...
M H, COTTLE +3 more
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DURING the last few years there has been a widespread increase in the clinical use of hyaluronidase, the specific enzyme now generally conceded to be the "spreading factor" of Duran-Reynals 1 and McClean. 2 Various authors have reported its effectiveness in facilitating the absorption of fluids by hypodermoclysis 3 and in effecting better local ...
M H, COTTLE +3 more
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Nature, 1948
DESPITE our deficient knowledge of the physical and chemical properties of both hyaluronic acid and hyaluronidase, it seems desirable to have a hyaluronidase unit, which can be used until international standard preparations are available for comparison, in order to be able to correlate the numerous investigations being carried out with this substance ...
S, DALGAARD-MIKKELSEN +2 more
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DESPITE our deficient knowledge of the physical and chemical properties of both hyaluronic acid and hyaluronidase, it seems desirable to have a hyaluronidase unit, which can be used until international standard preparations are available for comparison, in order to be able to correlate the numerous investigations being carried out with this substance ...
S, DALGAARD-MIKKELSEN +2 more
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Inhibitors of the hyaluronidases
Matrix Biology, 2002The inhibitors of hyaluronidase present in mammalian sera, first described half a century ago, have remained uncharacterized. Because of increased interest in hyaluronidases and their hyaluronan substrate, a study of these inhibitors was undertaken recently.
Kazuhiro, Mio, Robert, Stern
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Hyaluronidase and Chondroitinase
2016Glycosaminoglycans (GAGs) are important constituents of the extracellular matrix that make significant contributions to biological processes and have been implicated in a wide variety of diseases. GAG-degrading enzymes with different activities have been found in various animals and microorganisms, and they play an irreplaceable role in the structure ...
Wenshuang, Wang +2 more
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Nature, 1952
AN unsolved problem in the study of rheumatic diseases is whether or not hyaluronidase plays any part in the typical changes in the connective tissue, particularly of the interfibrillar cement substance, which is believed to contain hyaluronic acid.
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AN unsolved problem in the study of rheumatic diseases is whether or not hyaluronidase plays any part in the typical changes in the connective tissue, particularly of the interfibrillar cement substance, which is believed to contain hyaluronic acid.
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