Results 101 to 110 of about 6,552 (226)

N, S Co‐Doped Carbon Quantum Dots‐Riboflavin Composite Photosensitizers for Enhanced Iontophoresis‐Assisted Corneal Cross‐Linking

Advanced Science, EarlyView.
This study explores the use of N, S co‐doped carbon quantum dots (NS‐CQDs) as carriers for riboflavin, creating NS‐CQDs‐RF composite photosensitizers. These composites improve riboflavin absorption, enhance ROS generation efficiency, and preserve corneal epithelium integrity.
Tinghong Xu, Yong Liu, Wenjing Zhang, Qiuruo Jiang, Yi Jin, Liangzheng Lin, Lumeng Wang, Zhanhao Gu, Mimi Lin, Shihao Chen   +9 more
wiley   +1 more source

The Training Effect of Early Intervention with a Hybrid Assistive Limb after Total Knee Arthroplasty

Case Reports in Orthopedics, 2017
After total knee arthroplasty (TKA), it is important for patients to show early improvements in knee joint function and walking to regain independence in performing the activities of daily life. We conducted for 4 weeks an intervention one week after TKA
Takashi Fukaya, Hirotaka Mutsuzaki, Kenichi Yoshikawa, Ayumu Sano, Masafumi Mizukami, Masashi Yamazaki   +5 more
doaj   +1 more source

Design and validation of exoskeleton actuated by soft modules towards neurorehabilitation - vision-based control for precise reaching motion of upper limb [PDF]

, 2017
We demonstrated the design, production, and functional properties of the Exoskeleton Actuated by the Soft Modules (EAsoftM). Integrating the 3D printed exoskeleton with passive joints to compensate gravity and with active joints to rotate the shoulder ...
Chiri, Chiu, Denavit, Dovat, Hayashi, Henry Eberle, Heo, Hyejong Kim, Ilievski, Jack, Kim, Kondo, Krebs, Krebs, Kutner, Loureiro, Loureiro, Loureiro, Maciejasz, Marchese, Martinez, Nishida, Oguntosin, Polygerinos, Rahman, Sadao Kawamura, Sanchez, Schulz, Shepherd, Slawomir J. Nasuto, Sun, Takagi, Tondu, Tsagarakis, Ueki, Victoria W. Oguntosin, Yoshikatsu Hayashi, Yoshiki Mori   +37 more
core   +2 more sources

Cellular Snowballing: Cell Adhesion and Migration Drive the Self‐Assembly of Cell‐Microgel Biohybrid Spheroids

Advanced Science, EarlyView.
A new class of biohybrid spheroids is engineered through the self‐assembly of adherent cells and extracellular matrix‐mimetic hydrogel microparticles (microgels). By mimicking a snowballing effect, this approach enables scalable formation of porous, millimeter‐scale spheroids with enhanced cell viability and molecular diffusion.
Zaman Ataie, Sina Kheirabadi, Changhao Li, Aneesh Risbud, Aswathy Sebastian, Istvan Albert, Sulin Zhang, Amir Sheikhi   +7 more
wiley   +1 more source

Efficacy of exercise with the hybrid assistive limb lumbar type on physical function in mobility-limited older adults: A 5-week randomized controlled trial

Experimental Gerontology
Background: Sarcopenia and frailty often worsen in older adults because of declines in activities of daily living and social connections that are associated with chronic diseases and traumatic injuries such as falls and fractures.
Yoshinobu Saito, Sho Nakamura, Takashi Kasukawa, Makoto Nagasawa, Yuko Oguma, Hiroto Narimatsu   +5 more
doaj   +1 more source

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

Gait Rehabilitation Using Hybrid Assistive Limb in Patients With Lower Limb Amputation: Protocol for a Single-Arm Clinical Trial

JMIR Research Protocols
BackgroundLower limb amputation rates are increasing owing to aging and vascular diseases. However, no standardized rehabilitation protocol has been established for regaining walking ability.
Makoto Asaeda, Naoya Orita, Masashi Shimada, Yoshifumi Kono, Kiyo Ueda, Takeya Araki, Naoto Fujita, Yukio Mikami   +7 more
doaj   +1 more source

Elbow Joint Hybrid Assistive Limb Treatment Improves Upper Limb Dysfunction in Guillain-Barré Syndrome: A Case Report

Cureus
Robot-assisted rehabilitation is becoming an important option in rehabilitation medicine. We utilized one such device, the elbow joint hybrid assistive limb (HAL), for a patient with Guillain-Barré syndrome (GBS). The patient was a 64-year-old man, 16 months post-onset of GBS.
Hayashi, Koji, Matsuyama, Takumi, Sato, Mamiko, Suzuki, Asuka, Nakaya, Yuka, Takaku, Naoko, Miura, Toyoaki, Kobayashi, Yasutaka   +7 more
openaire   +2 more sources

Circular RNA circNrip1 Interacts with SYNCRIP to Promote Neuropathic Pain by Stabilizing Tlr2 mRNA in Primary Sensory Neurons

Advanced Science, EarlyView.
Model of circNrip1 (cNrip1) upregulation driving neuropathic pain mechanisms. After peripheral nerve injury, increased FUS triggers the formation and upregulation of cNrip1 in injured DRG neurons. Upregulated cNrip1 recruits SYNCRIP to the 3′‐UTR of Tlr2 mRNA by binding to both, thereby promoting SYNCRIP‐triggered Tlr2 mRNA stability and increasing ...
Xiaozhou Feng, Jifang Xiao, Congcong Huang, Bao‐Chun Jiang, Bing Wang, Xu Li, Shibin Du, Tolga Berkman, Chun‐Hsien Wen, Weihua Cai, Dilip Sharma, Kun Wang, Longfei Ma, Huijuan Hu, Yuan‐Xiang Tao   +14 more
wiley   +1 more source

Albumin‐Bound STING Agonist Reprograms HSPCs to Antitumor Neutrophils Enhancing CD8+ T Cell Immunity

Advanced Science, EarlyView.
This study demonstrates that an albumin‐bound STING agonist (Nano ZSA‐51D) reprograms HSPCs to produce antitumor neutrophils with enhanced MHC I–mediated CD8+ T cell activation, thereby sensitizing tumors to α‐PD1 therapy. These findings highlight a strategy to target early hematopoiesis for shaping neutrophil fate and potentiating cancer immunotherapy.
Jinsong Tao, Hong‐Yi Zhao, Chengyi Li, Hanning Wen, Fang Ke, Qiuxia Li, Miao He, Bo Wen, Zhongwei Liu, Kai Sun, Wei Gao, Duxin Sun   +11 more
wiley   +1 more source