Results 41 to 50 of about 1,639,929 (252)

Enhancing Metaheuristic Optimization: A Novel Nature-Inspired Hybrid Approach Incorporating Selected Pseudorandom Number Generators

open access: yesAlgorithms, 2023
In this paper, a hybrid nature-inspired metaheuristic algorithm based on the Genetic Algorithm and the African Buffalo Optimization is proposed. The hybrid approach adaptively switches between the Genetic Algorithm and the African Buffalo Optimization ...
Marko Gulić, Martina Žuškin
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

Study on Rock Breaking Characteristics of a Hybrid Bit

open access: yesShiyou jixie, 2020
Existing conventional PDC and roller bits are unable to meet the rock breaking requirements in deep and hard formations, difficult-to-drill formations and soft and hard formations.
吴泽兵   +4 more
doaj  

Machine Learning Inspired Hybrid Precoding for Wideband Millimeter-Wave Massive MIMO Systems

open access: yesIEEE Access, 2019
Millimeter-wave (mmWave) massive multiple-input multiple-output (MIMO) has already been considered as a promising solution to meet the requirement of the higher data rate for the future Internet of Things (IoTs). Hybrid precoding is an effective solution
Talha Mir   +4 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

open access: yesFEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar   +11 more
wiley   +1 more source

Methods of Drilling Speed Promotion for Several Typical Difficult Drilling Formations

open access: yesShiyou jixie, 2016
Considering the low ROP and short service life of PDC bit in extra-hard, strong abrasion and soft and hard interlayered heterogeneous formation, new drilling tools and methods are needed to address the drilling speed promotion challenge in difficult ...
Tong Jinwang
doaj  

Is an Apple an Orange? A Large Language Model Benchmark for Candidate Term Extraction and Subclass Decisions Against Upper Ontologies in Engineering and Materials Science

open access: yesAdvanced Engineering Materials, EarlyView.
Building machine‐readable vocabularies for materials science is slow, expert‐driven work. This study benchmarks 13 large language models on two of its first steps: finding candidate terms in engineering articles and deciding where they belong in a class hierarchy.
Thomas Bjarsch   +3 more
wiley   +1 more source

AstrobioMike/bit: v1.8.37

open access: yes, 2021
added bit-gen-iToL ...
Mike Lee
core   +1 more source

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