Results 41 to 50 of about 451,817 (286)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Molecular-level hybridization of single-walled carbon nanotubes and a copper complex with counterbalanced electrostatic interactions

Communications Materials
Hybridization and wet processibility are highly desired development strategies for next-generation nanomaterials. In particular, the hybridization of carbon nanotubes (CNTs) and transition metals has been investigated for decades owing to the numerous ...
Mi-Jeong Kim, Hyeonbeom Kim, Jungmo Kim, Yeo Jin Lee, Wonki Lee, Jun Yeon Hwang, Ki Kang Kim, Hee Jin Jeong   +7 more
doaj   +1 more source

Abrasive water jet drilling of advanced sustainable bio-fibre-reinforced polymer/hybrid composites : a comprehensive analysis of machining-induced damage responses [PDF]

, 2018
This paper aims at investigating the effects of variable traverse speeds on machining-induced damage of fibre-reinforced composites, using the abrasive water jet (AWJ) drilling.
A Alberdi, A Alberdi, A Hascalik, A Hascalik, A Hejjaji, AA Shaikh, B KC, DF Liu, DJ McGill, DJ Thomas, DJ Thomas, E Oho, FA Almansour, FL Chen, G Fowler, H Heidarya, H Ho-Cheng, H Hocheng, HN Dhakal, HN Dhakal, Hom Nath Dhakal, I Shyha, J Flynn, J Montesano, James R. Smith, JC Crocker, JK Patel, K Phapale, M Ramulu, Marco Paggi, MM Thwe, MMW Irina, N Ramesha, NE Hajj, PD Unde, R Selvam, S Kalirasu, S Nunna, Saheed Olalekan Ojo, Sikiru Oluwarotimi Ismail, SO Ismail, SO Ismail, SO Ismail, SP Jani, YW Seo   +44 more
core   +3 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Advanced fiber-composite hybrids--A new structural material [PDF]

, 1974
Introduction of metal foil as part of matrix and fiber composite, or ""sandwich'', improves strength and stiffness for multidirectional loading, improves resistance to cyclic loading, and improves impact and erosion resistance of resultant fiber ...
Chamis, C. C., Lark, R. F., Sullivan, T. L.   +2 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Effect of Environmental Degradation on Mechanical Properties of Kenaf/Polyethylene Terephthalate Fiber Reinforced Polyoxymethylene Hybrid Composite

Advances in Materials Science and Engineering, 2013
The main objective of this research is to investigate the effect of environmental degradation on the mechanical properties of kenaf/PET fiber reinforced POM hybrid composite.
Mohamad Zaki Abdullah, Yakubu Dan-mallam, Puteri Sri Melor Megat Yusoff   +2 more
doaj   +1 more source

UNIDIRECTIONAL HYBRID COMPOSITE OVERLOAD SENSORS [PDF]

, 2017
A purpose-designed, thin-ply interlayer glass/carbon hybrid composite overload sensor concept is presented, which can be used for structural health monitoring (SHM) of composite structures, with potential for safer operation in service.
Rev, T., Czél, G., Jalalvand, M., Wisnom, M. R.   +3 more
openaire   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source