Results 41 to 50 of about 335,173 (311)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

A Smart Polymer Composite Based on a NiTi Ribbon and a Magnetic Hybrid Material for Actuators with Multiphysic Transduction

open access: yesActuators, 2015
A smart composite material constituted of a magnetic hybrid film and a NiTi shape memory alloy (SMA) ribbon was obtained and characterized. The magnetic hybrid film was joined to the NiTi ribbon in order to combine the properties of both materials.
Beatriz López-Walle   +4 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

A Study on Effect of Variation of Thickness on Tensile Properties of Hybrid Polymer Composites (Glassfibre-Carbonfibre-Graphite) and GFRP Composites [PDF]

open access: yes, 2013
Increase in demand of advanced materials to satisfy the requirements of aerospace and automotive industry viz. high modulus to density ratio, leads to the research in composite materials where an attempt is made to study the ...
Nayeem Ahmed, M.   +3 more
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Investigating the influence of the constituent materials on the performance of periodic piezoelectric composite arrays [PDF]

open access: yes, 2007
This paper describes a theoretical investigation into the influence of the constituent materials on periodic composite array transducer performance. A finite element (FE) model, configured in PZFlex, is used to analyze the performance of a wedge coupled ...
Gachagan, A.   +3 more
core   +1 more source

Hybrid and composite materials of organic crystals

open access: yesChemical Science
Combining organic crystals and polymers results in a new class of all-organic, lightweight, flexible materials with unprecedented mechanical robustness, resilience, and diversity in combination with other functional materials.
Xuesong Yang   +4 more
openaire   +2 more sources

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Design, Synthesis and Characterization of Hybrid Composite Materials

open access: yesApplied Sciences, 2023
Polymer composites represent the platform materials of the 21st century, and they make up an important slice of the market for the production of modern materials [...]
Ignazio Blanco
doaj   +1 more source

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