Results 41 to 50 of about 10,301,713 (281)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Strengthening the resilience and adaptive capacity of societies at risk from hybrid threats [PDF]
, 2021 How would the civilian population of a specific country respond to significant disruptions caused by hybrid threats? This paper explores different response scenarios and considers what can be done to strengthen the resilience and adaptive capacities of a
de Coning, Cedric
core
JCO Global OncologyPURPOSEWe aimed to examine the impact of different conference formats (in-person, virtual, and hybrid) of the ASCO conference on greenhouse gas (GHG) emissions and to recommend sustainable options for future conferences.MATERIALS AND METHODSThis study ...
Katie E. Lichter +12 more
doaj +1 more source
Proceedings of the 2022 Cannabis Clinical Outcomes Research Conference
Medical Cannabis and Cannabinoids, 2022 The Consortium for Medical Marijuana Clinical Outcomes Research, a multi-university collaboration established by the state of Florida in the USA, hosted its second annual Cannabis Clinical Outcomes Research Conference (CCORC) in May 2022.
Nicole E. Smolinski +5 more
doaj +1 more source
Designing the Structure of a Hybrid Conference
, 2021 This paper presents the conceptual and technical setups of the recent Rhythm, Production and Perception Workshop (RPPW) 2021 hybrid conference. For this conference, there were adaptations to accommodate the effects of the COVID-19 pandemic which has prevailed since 2020.
openaire +2 more sources
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
University Library at a New Stage of Social Communications Development, 2020 A new (5th) issue of the journal “University Library at a New Stage of Social Communications Development. Conference Proceedings” is presented. Full-format papers were selected, reviewed and recommended by the members of the international editorial board
Tetiana O. KOLESNYKOVA
doaj +1 more source
The 14th International Conference of Students of Systematic Musicology (SysMus21)
Music & Science, 2022 The 14th International Conference of Students of Systematic Musicology (SysMus21) was held in a hybrid format that allowed both in-person and online participants to join.
Luca Kiss +4 more
doaj +1 more source