Results 51 to 60 of about 1,922,975 (296)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Hybrid Rocket Engine Ignition and Control [PDF]

open access: yes, 2020
Control of a hybrid rocket engine is dependent upon a robust system capable of executing commands at precise times. In order to accomplish this, hardware systems must be in place to control the flow of a pressurized gas and provide feedback to launch ...
Blampied, Trevor   +3 more
core   +1 more source

Nondeterministic Control for Hybrid Search [PDF]

open access: yesConstraints, 2005
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Van Hentenryck, Pascal, Michel, Laurent
openaire   +2 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Super-Twisting Hybrid Control for Ship-Borne PMSM

open access: yesIEEE Open Journal of Intelligent Transportation Systems, 2022
In the field of ship-borne PMSM, there exists the sea wave fluctuations, external disturbances thus model uncertainties are always challenging the control design of ship-borne permanent magnet synchronous motors (PMSMs).
Di-Fen Shi   +4 more
doaj   +1 more source

An earth pole-sitter using hybrid propulsion [PDF]

open access: yes, 2010
In this paper we investigate optimal pole-sitter orbits using hybrid solar sail and solar electric propulsion (SEP). A pole-sitter is a spacecraft that is constantly above one of the Earth's poles, by means of a continuous thrust.
Becerra V. M.   +8 more
core   +2 more sources

Stabilizing Dynamic Controllers for Hybrid Systems: A Hybrid Control Lyapunov Function Approach [PDF]

open access: yesIEEE Transactions on Automatic Control, 2014
This paper proposes a dynamic controller structure and a systematic design procedure for stabilizing discrete-time hybrid systems. The proposed approach is based on the concept of control Lyapunov functions (CLFs), which, when available, can be used to design a stabilizing state-feedback control law.
Di Cairano, Stefano   +3 more
openaire   +3 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Transfer Function-Based Road Classification for Vehicles with Nonlinear Semi-Active Suspension

open access: yesWorld Electric Vehicle Journal
Ride comfort and handling are two important criteria regarding vehicle vibration control. For solving the inconsistency between ride comfort and handling, a semi-active suspension system equipped with a road classification system can be a suitable ...
Hamed Kouhi   +3 more
doaj   +1 more source

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