Results 61 to 70 of about 14,555,344 (255)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Battery, Hybrid and Fuel-Cell Propulsion Systems [PDF]
, 2011 The main purpose of the Research is theoretical and experimental evaluation of electric propulsion systems: pure electric ones, fed exclusively by electrochemical energy storage, hybrid electric, in which the power for propulsion comes from different ...
LUTZEMBERGER, GIOVANNI
core
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Design of alternative energy storage systems for hybrid vehicles based on statistical processing of driving cycles information [PDF]
, 2011 Hybrid vehicles represent the future for automakers, since they allow to improve the fuel economy and to reduce the pollutant emissions. A key component of the hybrid powertrain is the Energy Storage System, that determines the ability of the vehicle to ...
Bolletta, Alberto
core
Comparative performance and thermoeconomic analyses of high temperature polymer electrolyte membrane based two hybrid systems [PDF]
, 2021 The main objective of this study is to compare the two systems in terms of the thermoeconomic and the performance. The first one is called hybrid I and consists of high temperature polymer electrolyte membrane and thermocapacitive cycle.
Erzen, S.
core +1 more source
Optimization of Renewable Energy Hybrid System for Grid Connected Application
Rona Teknik Pertanian, 2012 . Hybrid energy systems are pollution free, takes low cost and less gestation period, user and social friendly. Such systems are important sources of energy for shops, schools, and clinics in village communities especially in remote areas. Hybrid systems
Mustaqimah Mustaqimah
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Summary Report of the INL-JISEA Workshop on Nuclear Hybrid Energy Systems [PDF]
, 2012 The Institute for Nuclear Energy Science and Technology (INEST) and the Joint Institute for Strategic Energy Analysis (JISEA) co-sponsored an international workshop to identify research topics important in advancing the potential use of hybrid systems ...
Cherry, R. +5 more
core +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source