Results 41 to 50 of about 111,050 (304)

Efficiency of the solution representations for the hybrid flow shop scheduling problem with makespan objective [PDF]

open access: yes, 2019
In this paper we address the classical hybrid flow shop scheduling problem with makespan objective. As this problem is known to be NP-hard and a very common layout in real-life manufacturing scenarios, many studies have been proposed in the literature to
Fernández-Viagas Escudero, Víctor   +2 more
core  

A new adaptive neural network and heuristics hybrid approach for job-shop scheduling [PDF]

open access: yes, 2001
Copyright @ 2001 Elsevier Science LtdA new adaptive neural network and heuristics hybrid approach for job-shop scheduling is presented. The neural network has the property of adapting its connection weights and biases of neural units while solving the ...
Baker   +18 more
core   +2 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A Hybrid Metaheuristic Approach for Minimizing the Total Flow Time in A Flow Shop Sequence Dependent Group Scheduling Problem

open access: yesAlgorithms, 2014
Production processes in Cellular Manufacturing Systems (CMS) often involve groups of parts sharing the same technological requirements in terms of tooling and setup. The issue of scheduling such parts through a flow-shop production layout is known as the
Antonio Costa   +2 more
doaj   +1 more source

Efficient heuristics for the hybrid flow shop scheduling problem with missing operations [PDF]

open access: yes, 2019
In this paper, we address the hybrid flowshop scheduling problem for makespan minimisation. More specifically, we are interested in the special case where there are missing operations, i.e.
Dios, Manuel   +2 more
core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Hybridization of Particle Swarm Optimization with Variable Neighborhood Search and Simulated Annealing for Improved Handling of the Permutation Flow-Shop Scheduling Problem

open access: yesSystems, 2023
Permutation flow-shop scheduling is the strategy that ensures the processing of jobs on each subsequent machine in the exact same order while optimizing an objective, which generally is the minimization of makespan.
Iqbal Hayat   +6 more
doaj   +1 more source

On the use of biased-randomized algorithms for solving non-smooth optimization problems [PDF]

open access: yes, 2020
Soft constraints are quite common in real-life applications. For example, in freight transportation, the fleet size can be enlarged by outsourcing part of the distribution service and some deliveries to customers can be postponed as well; in inventory ...
Ferrer Biosca, Albert   +4 more
core   +3 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

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