Phylogenetic and Chemical Diversity of a Hybrid-Isoprenoid-Producing Streptomycete Lineage [PDF]
ABSTRACT Streptomyces species dedicate a large portion of their genomes to secondary metabolite biosynthesis. A diverse and largely marine-derived lineage within this genus has been designated MAR4 and identified as a prolific source of hybrid isoprenoid (HI) secondary metabolites. These terpenoid-containing compounds
Gallagher, Kelley A +3 more
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Hybrid cells differentiate to hepatic lineage cells and repair oxidative damage [PDF]
AbstractHybrid cells derived from stem cells play an important role in organogenesis, tissue regeneration and cancer formation. However, the fate of hybrid cells and their range of function are poorly understood. Fusing stem cells and somatic cells induces somatic cell reprogramming, and the resulting hybrid cells are embryonic stem cell-like cells ...
Xu, Dan +6 more
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Genomic Analysis Confirms Population Structure and Identifies Inter-Lineage Hybrids in Aegilops tauschii [PDF]
Aegilops tauschii, the D-genome donor of bread wheat, Triticum aestivum, is a storehouse of genetic diversity, and an important resource for future wheat improvement. Genomic and population analysis of 549 Ae.
Narinder Singh +8 more
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Interspecific hybrid lethality and sterility are a consequence of divergent evolution between species and serve to maintain the discrete identities of species.
Daniel A Barbash +2 more
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Revealing the Detailed Lineage of Script Outputs Using Hybrid Provenance [PDF]
We illustrate how combining retrospective and prospectiveprovenance can yield scientifically meaningful hybrid provenancerepresentations of the computational histories of data produced during a script run.
Qian Zhang +10 more
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Engineered Murine HSCs Reconstitute Multi-lineage Hematopoiesis and Adaptive Immunity
Hematopoietic stem cell (HSC) transplantation is curative for malignant and genetic blood disorders, but is limited by donor availability and immune-mismatch.
Yi-Fen Lu +10 more
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Systems genetic analysis of osteoblast-lineage cells.
The osteoblast-lineage consists of cells at various stages of maturation that are essential for skeletal development, growth, and maintenance. Over the past decade, many of the signaling cascades that regulate this lineage have been elucidated; however ...
Gina Calabrese +8 more
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Sex chromosome turnover in hybridizing stickleback lineages
Abstract Recent discoveries of sex chromosome diversity across the tree of life have challenged the canonical model of conserved sex chromosome evolution and evoked new theories on labile sex chromosomes that maintain less differentiation and undergo frequent turnover.
Xueling Yi +5 more
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Natural hybridization generates mammalian lineage with species characteristics [PDF]
Most diploid species arise from single-species ancestors. Hybrid origins of new species are uncommon (except among polyploids) and are documented infrequently in animals. Examples of natural hybridization leading to speciation in mammals are exceedingly rare.
Peter A, Larsen +2 more
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DNA hybridization evidence for the principal lineages of hummingbirds (Aves:Trochilidae) [PDF]
The spectacular evolutionary radiation of hummingbirds (Trochilidae) has served as a model system for many biological studies. To begin to provide a historical context for these investigations, we generated a complete matrix of DNA hybridization distances among 26 hummingbirds and an outgroup swift (Chaetura pelagica) to determine the principal ...
R, Bleiweiss, J A, Kirsch, J C, Matheus
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