Results 11 to 20 of about 49,201 (297)

Phylogenetic and Chemical Diversity of a Hybrid-Isoprenoid-Producing Streptomycete Lineage [PDF]

open access: yesApplied and Environmental Microbiology, 2013
ABSTRACT Streptomyces species dedicate a large portion of their genomes to secondary metabolite biosynthesis. A diverse and largely marine-derived lineage within this genus has been designated MAR4 and identified as a prolific source of hybrid isoprenoid (HI) secondary metabolites. These terpenoid-containing compounds
Gallagher, Kelley A   +3 more
openaire   +6 more sources

Hybrid cells differentiate to hepatic lineage cells and repair oxidative damage [PDF]

open access: yesCellular and Molecular Biology Letters, 2010
AbstractHybrid cells derived from stem cells play an important role in organogenesis, tissue regeneration and cancer formation. However, the fate of hybrid cells and their range of function are poorly understood. Fusing stem cells and somatic cells induces somatic cell reprogramming, and the resulting hybrid cells are embryonic stem cell-like cells ...
Xu, Dan   +6 more
openaire   +3 more sources

Genomic Analysis Confirms Population Structure and Identifies Inter-Lineage Hybrids in Aegilops tauschii [PDF]

open access: yesFrontiers in Plant Science, 2019
Aegilops tauschii, the D-genome donor of bread wheat, Triticum aestivum, is a storehouse of genetic diversity, and an important resource for future wheat improvement. Genomic and population analysis of 549 Ae.
Narinder Singh   +8 more
doaj   +2 more sources

Functional divergence caused by ancient positive selection of a Drosophila hybrid incompatibility locus.

open access: yesPLoS Biology, 2004
Interspecific hybrid lethality and sterility are a consequence of divergent evolution between species and serve to maintain the discrete identities of species.
Daniel A Barbash   +2 more
doaj   +2 more sources

Revealing the Detailed Lineage of Script Outputs Using Hybrid Provenance [PDF]

open access: yesInternational Journal of Digital Curation, 2018
We illustrate how combining retrospective and prospectiveprovenance can yield scientifically meaningful hybrid provenancerepresentations of the computational histories of data produced during a script run.
Qian Zhang   +10 more
doaj   +3 more sources

Engineered Murine HSCs Reconstitute Multi-lineage Hematopoiesis and Adaptive Immunity

open access: yesCell Reports, 2016
Hematopoietic stem cell (HSC) transplantation is curative for malignant and genetic blood disorders, but is limited by donor availability and immune-mismatch.
Yi-Fen Lu   +10 more
doaj   +2 more sources

Systems genetic analysis of osteoblast-lineage cells.

open access: yesPLoS Genetics, 2012
The osteoblast-lineage consists of cells at various stages of maturation that are essential for skeletal development, growth, and maintenance. Over the past decade, many of the signaling cascades that regulate this lineage have been elucidated; however ...
Gina Calabrese   +8 more
doaj   +2 more sources

Sex chromosome turnover in hybridizing stickleback lineages

open access: yesEvolution Letters, 2023
Abstract Recent discoveries of sex chromosome diversity across the tree of life have challenged the canonical model of conserved sex chromosome evolution and evoked new theories on labile sex chromosomes that maintain less differentiation and undergo frequent turnover.
Xueling Yi   +5 more
openaire   +3 more sources

Natural hybridization generates mammalian lineage with species characteristics [PDF]

open access: yesProceedings of the National Academy of Sciences, 2010
Most diploid species arise from single-species ancestors. Hybrid origins of new species are uncommon (except among polyploids) and are documented infrequently in animals. Examples of natural hybridization leading to speciation in mammals are exceedingly rare.
Peter A, Larsen   +2 more
openaire   +3 more sources

DNA hybridization evidence for the principal lineages of hummingbirds (Aves:Trochilidae) [PDF]

open access: yesMolecular Biology and Evolution, 1997
The spectacular evolutionary radiation of hummingbirds (Trochilidae) has served as a model system for many biological studies. To begin to provide a historical context for these investigations, we generated a complete matrix of DNA hybridization distances among 26 hummingbirds and an outgroup swift (Chaetura pelagica) to determine the principal ...
R, Bleiweiss, J A, Kirsch, J C, Matheus
openaire   +2 more sources

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