Results 71 to 80 of about 3,764,677 (378)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Microstructure transformations and improving wear resistance of austenitic stainless steel additively fabricated by arc-based DED process

Defence Technology
In this study, austenitic stainless steel (ASS) was additively fabricated by an arc-based direct energy deposition (DED) technique. Macrostructure, microstructure, mechanical characteristics at different spatial orientations (0°, 90°, and 45°), and wear ...
Ashish Yadav, Manu Srivastava, Prashant K. Jain, Sandeep Rathee   +3 more
doaj   +1 more source

Latest Developments in Industrial Hybrid Machine Tools that Combine Additive and Subtractive Operations [PDF]

, 2018
Hybrid machine tools combining additive and subtractive processes have arisen as a solution to increasing manufacture requirements, boosting the potentials of both technologies, while compensating and minimizing their limitations.
Arrizubieta Arrate, Jon Iñaki, Cortina Burón, Magdalena, Lamikiz Mentxaka, Aitzol, Ruiz Salas, José Exequiel, Ukar Arrien, Eneko   +4 more
core   +2 more sources

Hybrid manufacturing of titanium Ti-6Al-4V combining laser metal deposition and cryogenic milling

The International Journal of Advanced Manufacturing Technology, 2020
Hybrid manufacturing, which, e.g., combines additive manufacturing with conventional machining processes, can be a way of overcoming limitations currently encountered in additive manufacturing.
J. Moritz, A. Seidel, M. Kopper, J. Bretschneider, J. Gumpinger, Thomas Finaske, M. Riede, Michael Schneeweiß, E. López, F. Brückner, C. Leyens, T. Rohr, T. Ghidini   +12 more
semanticscholar   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Hot forming behavior of tungsten carbide reinforced Ni-Based superalloy 625 additively manufactured by laser directed energy deposition

Additive Manufacturing Letters
The demands of high-performance industries such as aerospace, automotive, tool manufacturing, oil, and gas industries are driving the innovation in high-performance materials and their production methods.
Gökhan Ertugrul, Aliakbar Emdadi, Angelika Jedynak, Sabine Weiß, Sebastian Härtel   +4 more
doaj   +1 more source

2D characterisation and evaluation of multi-material structures towards 3D hybrid printing

Virtual and Physical Prototyping, 2023
Multi-material manufacturing through the hybridisation of printed electronics and additive manufacturing has gained great interest recently. However, such hybridisation attempts are not trivial due to the need for functional material development and ...
Umur I. Cicek, Darren J. Southee, Andrew A. Johnson   +2 more
doaj   +1 more source

Opening New Opportunities For Aeronautic, Naval And Train Large Components Realization With Hybrid And Twin Manufacturing

Journal of Machine Engineering, 2022
Additive Manufacturing proposes innovative directions for high value components and has benefitted from large research efforts for almost all existing industrial sectors.
Matthieu Rauch, Jean-Yves Hascoet
doaj   +1 more source

The potential of additive manufacturing in the smart factory industrial 4.0: A review [PDF]

, 2019
Additive manufacturing (AM) or three-dimensional (3D) printing has introduced a novel production method in design, manufacturing, and distribution to end-users.
Dehghanghadikolaei, Amir, Emamian, Sattar S., Fotovvati, Behzad, Gisario, Annamaria, Mehrpouya, Mehrsha, Vosooghnia, Alireza   +5 more
core   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source