Results 41 to 50 of about 2,166,508 (336)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
System approach to building a mathematical model of a complex organizational-technical system in transport [PDF]
ITM Web of ConferencesThe current situation in the synthesis of complex organizational and technical systems in transport is characterized by a significant lag in the level of development of special mathematical and software, which significantly reduces the pace of ...
Zhukov Aleksandr +4 more
doaj +1 more source
Minimal Rank Properties of Outer Inverses with Prescribed Range and Null Space
Mathematics, 2023 The purpose of this paper is to investigate solvability of systems of constrained matrix equations in the form of constrained minimization problems.
Dijana Mosić +2 more
doaj +1 more source
GPU-accelerated discontinuous Galerkin methods on hybrid meshes
, 2015 We present a time-explicit discontinuous Galerkin (DG) solver for the time-domain acoustic wave equation on hybrid meshes containing vertex-mapped hexahedral, wedge, pyramidal and tetrahedral elements.
Chan, Jesse +4 more
core +3 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
A model for describing the administration and processing system of information generated when responding to incidents by fire departments [PDF]
ITM Web of ConferencesFirefighting units are a specific object of management that performs its functions in response in conditions of limited time and intensive flow of information.
Gelek Sergey +2 more
doaj +1 more source
Construction and analysis of causally dynamic hybrid bond graphs [PDF]
, 2013 Engineering systems are frequently abstracted to models with discontinuous behaviour (such as a switch or contact), and a hybrid model is one which contains continuous and discontinuous behaviours.
Asher GM +23 more
core +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Hybrid Monte Carlo-Methods in Credit Risk Management
, 2014 In this paper we analyze and compare the use of Monte Carlo, Quasi-Monte Carlo and hybrid Monte Carlo-methods in the credit risk management system Credit Metrics by J.P.Morgan.
Del Chicca, Lucia, Larcher, Gerhard
core +1 more source
Hybrid image representation methods for automatic image annotation: a survey [PDF]
, 2012 In most automatic image annotation systems, images are represented with low level features using either global methods or local methods. In global methods, the entire image is used as a unit.
Bechkoum, Kamal +3 more
core +1 more source