Microwave Detection of Brain Injuries by Means of a Hybrid Imaging Method
Brain injuries represent a critical situation, where both detection and monitoring should be quick and accurate at the same time. Microwave techniques are thus gaining attention in the diagnostic process of these diseases.
Alessandro Fedeli +3 more
doaj +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Neuroinflammation in GAD65 Antibody‐Associated Epilepsy Measured Using [18F]DPA‐714 PET/MRI
ABSTRACT The timing for initiating immunotherapy in patients with glutamic acid decarboxylase 65 (GAD65) antibody‐associated epilepsy is a challenge. We used the translocator protein radioligand [18F]DPA‐714 and PET to evaluate brain microglial activation.
Jingjing Chen +10 more
wiley +1 more source
APPLICATION OF HYBRID RANDOM SEARCH METHOD TO OPTIMISATION OF ENGINEERING SYSTEMS’ PARAMETERS
This paper presents a modification of the Luus-Jaakola global optimization method, which belongs to the class of metaheuristic algorithms. A hybrid method is suggested, using a combination of random search methods: Luus-Jaakola method, adaptive random ...
A. V. Panteleev, D. A. Rodionova
doaj +1 more source
Explicit, implicit, and hybrid methods [PDF]
Time integration methods can be separated into two groups: explicit and implicit. Methods which do not involve the solution of any algebraic equations are called explicit, while those that require the solution of equations are called implicit.
Belytschko, T.
core +1 more source
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick +19 more
wiley +1 more source
Hybrid neural network framework for efficient solutions of third-order differential equations [PDF]
Over the years and across various scientific fields, artificial neural networks (ANN) have achieved remarkable success. Among these is deep feedforward neural networks (FFNNs) which notably enhanced the accuracy of numerous tasks.
Sabastine Emmanuel +2 more
doaj +1 more source
Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli +5 more
wiley +1 more source
Do You Want to Build a Genome? Benchmarking Hybrid Bacterial Genome Assembly Methods
Georgia Breckell, Olin Silander
openalex +1 more source

