Results 81 to 90 of about 35,975,054 (321)
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Radiative Transfer in Star Formation: Testing FLD and Hybrid Methods
We perform a comparison between two radiative transfer algorithms commonly employed in hydrodynamical calculations of star formation: grey flux limited diffusion and the hybrid scheme, in addition we compare these algorithms to results from the Monte ...
B. Ercolano +7 more
core +1 more source
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
Credit and Loan Approval Classification Using a Bio-Inspired Neural Network
Numerous people are applying for bank loans as a result of the banking industry’s expansion, but because banks only have a certain amount of assets to lend to, they can only do so to a certain number of applicants. Therefore, the banking industry is very
Spyridon D. Mourtas +3 more
doaj +1 more source
Hybrid molecular-continuum methods for micro- and nanoscale liquid flows [PDF]
This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
2nd Micro and Nano Flows Conference (MNF2009) +3 more
core
Optimized Quantification of Spin Relaxation Times in the Hybrid State
Purpose: The analysis of optimized spin ensemble trajectories for relaxometry in the hybrid state. Methods: First, we constructed visual representations to elucidate the differential equation that governs spin dynamics in hybrid state.
Assländer, Jakob +3 more
core +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Automatic 3-D Building Model Reconstruction from Very High Resolution Stereo Satellite Imagery
Recent advances in the availability of very high-resolution (VHR) satellite data together with efficient data acquisition and large area coverage have led to an upward trend in their applications for automatic 3-D building model reconstruction which ...
Tahmineh Partovi +4 more
doaj +1 more source
Hybrid Molecular Mechanics/Coarse-Grained (MM/CG) simulations help predict ligand poses in human G protein-coupled receptors (hGPCRs), the most important protein superfamily for pharmacological applications.
Jakob Schneider +10 more
doaj +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source

