Results 211 to 220 of about 143,062 (268)
Advanced Healthcare Materials, EarlyView.This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz +9 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.A biocompatible sodium alginate‐based hydrogel is developed as a next‐generation submucosal lifting agent intended for EMR and ESD. The optimized formulation exhibits a composition devoid of endotoxins, high viscosity, demonstrates reliable injectability, and ensures prolonged mucosal elevation.
Iram Maqsood +9 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Efficient recovery from traumatic or degenerative diseases is a great challenge, even after all the advancements in bone and cartilage regeneration. Machine learning (ML) algorithms have presented opportunities to enhance these aspects by accurately analyzing imaging data.
Maryam Kamaei +9 more
wiley +1 more source
Encoded Cell‐Material Interactions to Reroute Cytokine Signaling for Regenerative Medicine
Advanced Healthcare Materials, EarlyView.We present native MATRIX (Material Activated To Regulate Inducible gene eXpression), a co‐engineered material‐cell platform. Surfaces functionalized with antibodies for endogenous soluble ligands (e.g., IL‐1β or IL‐6) capture and immobilize ligands for presentation to a cognate, engineered synthetic Notch receptor, releasing a transcription factor (TF)
Zachary M. Eidman +7 more
wiley +1 more source
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Modeling hybridization kinetics
Mathematical Biosciences, 2003Formation of complementary base pairs between nucleic acids over a short region (
Wang, Jian-Ying, Drlica, Karl
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Competitive hybridization models
Physical Review E, 2010Microarray technology, in its simplest form, allows one to gather abundance data for target DNA molecules, associated with genomes or gene-expressions, and relies on hybridizing the target to many short probe oligonucleotides arrayed on a surface. While for such multiplexed reactions conditions are optimized to make the most of each individual probe ...
Vera, Cherepinsky +2 more
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Hybrid Model of Erythropoiesis
Acta Biotheoretica, 2013A hybrid model of cell dynamics is presented. It is illustrated by model examples and applied to study erythropoiesis (red blood cell production). In this approach, cells are considered as discrete objects while intra-cellular proteins and extra-cellular biochemical substances are described with continuous models. Spatial organization of erythropoiesis
P, Kurbatova, N, Eymard, V, Volpert
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2002
The modeling and simulation of physical systems is of key importance in many areas of science and engineering, and thus can benefit from high-quality software tools. In previous research we have demonstrated how functional programming can form the basis of an expressive language for causal hybrid modeling and simulation. There is a growing realization,
Henrik Nilsson +2 more
openaire +1 more source
The modeling and simulation of physical systems is of key importance in many areas of science and engineering, and thus can benefit from high-quality software tools. In previous research we have demonstrated how functional programming can form the basis of an expressive language for causal hybrid modeling and simulation. There is a growing realization,
Henrik Nilsson +2 more
openaire +1 more source