Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans +7 more
wiley +1 more source
Hybrid analysis of photovoltaic energy data containing excessive structural zeros. [PDF]
Altinişik Y +4 more
europepmc +1 more source
Upon contact with plasma, lipid nanoparticles (LNPs) rapidly acquire a protein corona (PC) that redefines their biological identity. In calcium‐containing environments, these coronated particles trigger the formation of a gel‐like plasma network, profoundly altering their transport properties and reducing their effective availability.
Serena Renzi +14 more
wiley +1 more source
Hybrid bioelectrochemical process enables hierarchical C, N, and P utilization towards negative carbon emission wastewater treatment. [PDF]
Li C +6 more
europepmc +1 more source
Magnetically responsive nanoparticles enable remote control over biomaterials, cells, and engineered tissues. This review summarizes material design, biological safety, fabrication and actuation strategies, computational validation, and translational pathways that support the development of magnetic tissue‐engineering platforms and future magnetically ...
Konstantinos Ioannidis +8 more
wiley +1 more source
A comparison of methods for designing hybrid type 2 cluster-randomized trials with continuous effectiveness and implementation endpoints. [PDF]
Owen MA, Li F, Liu R, Spiegelman D.
europepmc +1 more source
Optical Detection of Cellular Signals at Material Interfaces
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren +5 more
wiley +1 more source
Software-Defined UHF RFID Asset Tracking in Metallic Aircraft Cabins via IMU-Assisted Adaptive Kalman Filtering and Distilled Edge Intelligence. [PDF]
Karadag M, Pinarer O.
europepmc +1 more source
Preparation of RVG‐modified erythrocyte membrane‐coated HMPB nanocarriers loaded with L‐arginine and NBP (RM@HPAN) and its neuroprotective mechanism. After intravenous injection, RM@HPAN achieves prolonged circulation, RVG‐29‐mediated BBB penetration, and ischemic accumulation.
Shaofa Li +9 more
wiley +1 more source
A group brain-controlled method for UAVs using a hybrid paradigm of hand movements and visual evoked potentials. [PDF]
Li R +6 more
europepmc +1 more source

