Results 51 to 60 of about 2,126,715 (293)

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

open access: yesFEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav   +4 more
wiley   +1 more source

Between democracy and authoritarianism. Typology of hybrid regimes with emphasis on the concept of competitive authoritarianism [PDF]

open access: yes, 2011
The diploma paper addresses an issue of a discussion about hybrid regimes, which deals with problems of hard classification of regimes on scale of democracy, authoritarianism.
Drahokoupil, Štěpán
core  

TRANSPARENT THEY ENDURE: CAUSES AND CONSEQUENCES OF FISCAL TRANSPARENCY IN HYBRID REGIMES

open access: yes, 2017
This dissertation examines the causes of budget transparency in hybrid regimes and the impact of this transparency on political processes and government accountability in these regimes.
Ghazal Poshtkouhian Nadi (16749987)
core   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

open access: yesFEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata   +3 more
wiley   +1 more source

Anti-Regime Movements in Illiberal Regimes in East-Central Europe: a Theoretical Model

open access: yesPartecipazione e Conflitto
The paper introduces an ideal type of anti-regime movements against illiberal regimes in East-Central Europe, employing the Weberian concept of the ideal type as a theoretical model. These movements aim to constrain regime building, restructure political
Dániel Mikecz
doaj   +3 more sources

Monetary Policy in Hybrid Regimes

open access: yesIMF Working Papers, 2014
This paper analyzes the monetary policy framework in Kazakhstan. The authorities have been successful in containing inflation in the context of a managed exchange rate regime. Over the past two years, the central bank has taken steps to enhance its ability to regulate liquidity in the financial system. However, the current policy interest rate does not
Natan P. Epstein, Rafael Portillo
openaire   +2 more sources

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

open access: yesFEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli   +2 more
wiley   +1 more source

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

open access: yesFEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt   +2 more
wiley   +1 more source

Political Participation and Regime Stability : A Framework for Analyzing Hybrid Regimes

open access: yes, 2009
In past decades a number of countries that have moved away from outright authoritarianism have not transformed into democracies, but rather into regimes that combine democratic and non-democratic characteristics, sometimes labeled hybrid regimes.
Ekman, Joakim,, Joakim Ekman
core   +1 more source

Home - About - Disclaimer - Privacy