Results 121 to 130 of about 1,381,095 (238)
Advanced Science, EarlyView.This study developed a dual‐targeting biomimetic nanozyme hybrid system (Cu‐CeO2@ABs‐FTP) and integrated it with HAMA hydrogel to fabricate a microneedle patch (CAF@MN). The patch promotes fibroblast‐mediated wound repair, targets macrophages to induce M2 polarization, and targets myofibroblasts to exert anti‐fibrotic effects, thereby enabling rapid ...
Hongyi Zhang +14 more
wiley +1 more source
Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies
Advanced Science, EarlyView.This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan +5 more
wiley +1 more source
Advanced Science, EarlyView.A root‐inspired microneedle array patch uses lattice‐based mechanical interlocking to unite rigid microneedles with a flexible substrate. The interlocked rigid–soft architecture improves interfacial bonding, supports stable adhesion on curved and wet tissues under dynamic motion, and provides a versatile platform for robust biointerfacing and future ...
Jongchan Lee +9 more
wiley +1 more source
Switching Spike Plasticity Shapes ACE2 Engagement Across SARS‐CoV‐2 Variants
Advanced Science, EarlyView.Conformational plasticity governs SARS‐CoV‐2 spike function and ACE2 recognition. Using high‐speed AFM and single‐molecule force spectroscopy, we analyzed the ancestral spike and nine variants, revealing progressive rigidification from Delta, variable plasticity in Omicron sublineages, and JN.1 compaction.
Sarah Stainer +17 more
wiley +1 more source
Male sterile 44 confers dominant male sterility in maize by disrupting lipid metabolism pathways
Industrial Crops and ProductsDominant genic male sterility (DGMS) is a valuable trait for harnessing heterosis in hybrid breeding of industrial crops, yet its underlying molecular mechanisms remain poorly understood.
Zheng Liu +8 more
doaj +1 more source
Advanced Science, EarlyView.AM symbiosis induces GhWAK13 to promote fungal colonization. GhNTF3 negatively regulates symbiosis by promoting SA biosynthesis. GhWAK13 sequesters GhNTF3 at the membrane, limiting its nuclear translocation and relieving SA‐mediated suppression. Under Verticillium stress, GhNTF3 enters the nucleus and interacts with GhJAZ6 to activate SA signaling ...
Shuangjie Jia +10 more
wiley +1 more source
Advanced Science, EarlyView.The Tuta absoluta salivary effector TaCRVP subverts tomato immunity by hijacking host catalase SlCAT2. Through a sophisticated dual mechanism, TaCRVP simultaneously promotes SlCAT2 tetramerization for activation and blocks its SlAdBiL‐mediated degradation for stabilization.
Jianquan Yan +9 more
wiley +1 more source
Two Tightly Linked Genes at the hsa1 Locus Cause Both F 1 and F 2 Hybrid Sterility in Rice
Molecular mechanisms of hybrid breakdown associated with sterility (F_2 sterility) are poorly understood as compared with those of F_1 hybrid sterility.
Kubo, Takahiko +12 more
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Advanced Science, EarlyView.Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen +13 more
wiley +1 more source
Improving maize hybrid seed production through optimized male sterility systems
Cytoplasmic male sterility (CMS) and nuclear male sterility genes (ms-genes) are key components in the production of hybrid maize seed. The aim of this study is to analyze different male sterility systems and their potential application for producing ...
Todorović, Goran +6 more
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