Results 161 to 170 of about 1,381,095 (238)

Natural variation in the zinc-finger-encoding exon of Prdm9 affects hybrid sterility phenotypes in mice. [PDF]

Genetics
AbuAlia KFN, Damm E, Ullrich KK, Mukaj A, Parvanov E, Forejt J, Odenthal-Hesse L.   +6 more
europepmc   +1 more source

Hybrid Sterility with Meiotic Metaphase Arrest in Intersubspecific Mouse Crosses. [PDF]

J Hered, 2019
Nishino R, Petri S, Handel MA, Kunieda T, Fujiwara Y.   +4 more
europepmc   +1 more source

Cytoplasmic male sterility (CMS) in hybrid breeding in field crops

, 2016
Harnessing hybrid vigor or heterosis is a promising approach to tackle the current challenge of sustaining enhanced yield gains of field crops. In the context, cytoplasmic male sterility (CMS) owing to its heritable nature to manifest non-functional male
Singh, N.P., Jha, U.C., Adhimoolam, P., Bohra, A., Bisht, D.   +4 more
core  

An Injectable and Self‐Reinforced Piezoelectric Hydrogel for Irregular Bone Defects Regeneration: Dynamic Epigenetic Regulation Approach

Advanced Science, EarlyView.
An injectable and self‐reinforcing RSF‐based piezoelectric hydrogel conforms to irregular bone defects and progressively strengthens in situ, overcoming the trade‐off between injectability and mechanical stability. Mechanical loading generates bioelectrical cues that promote P300‐mediated H3K9 acetylation and upregulate PTH1R expression, thereby ...
Yu‐Kai Huang, Juan Li, Miao‐Miao Yang, Chao Jia, Quan‐Xin Gong, Guang‐Cheng Yuan, Dong Zhou, Wen‐Hui Shen, Zeng‐Gan Chen, Zhi‐Rui Dong, Jin‐Wang Huang, Jie Peng, Di‐Han Su, Ming‐Dong Zhao, Jian Dong, Li‐Bo Jiang   +15 more
wiley   +1 more source

piRNA silencing contributes to interspecies hybrid sterility and reproductive isolation in Drosophila melanogaster. [PDF]

Nucleic Acids Res, 2019
Kotov AA, Adashev VE, Godneeva BK, Ninova M, Shatskikh AS, Bazylev SS, Aravin AA, Olenina LV.   +7 more
europepmc   +1 more source

Degrading GPX4 via Biomimetic Nanoparticle‐Mediated In Situ Synthesis of Deep‐Learning‐Designed Binder‐Degron Chimeras for Prostate Cancer Therapy

Advanced Science, EarlyView.
A deep‐learning‐designed binder is fused to a combinatorial degron to create a binder‐degron chimera (bdC) that recruits the CUL2‐RING ubiquitin ligase complex. Encapsulation in a prostate‐cancer‐targeted, CD47‐camouflaged nanocarrier enables tumor‐specific in situ bdC expression, triggering GPX4 degradation and ferroptosis, thereby establishing a ...
Si‐Han Zhang, Ye An, Na Zeng, Mei‐Cheng Liu, Jian‐Xuan Sun, Xi Gong, Jin‐Zhou Xu, Shao‐Gang Wang, Qi‐Dong Xia   +8 more
wiley   +1 more source

A Scalable Droplet Microfluidic Platform That Overcomes Large‐Cell Constraints for Long‐Term Plant Cell Culture and Embryogenesis Analysis

Advanced Science, EarlyView.
This work presents a large‐cell‐compatible droplet microfluidic platform that overcomes long‐standing barriers in plant cell culture by enabling high‐fidelity encapsulation, novel multilayer 3D droplet incubation for scalable long‐term culture, and support for the full developmental progression of large plant cells.
Arman Mirmiran, Fangchi Shao, Gregory Datto, Tathansh Joshi, Elizabeth Chatt, Yashar Bashirzadeh, Dan Stessman, Lai Wei, Kuangwen Hsieh, Hena Guo, Tza‐Huei Wang   +10 more
wiley   +1 more source

OlCHR, encoding a chromatin remodeling factor, is a killer causing hybrid sterility between rice species Oryza sativa and O. longistaminata. [PDF]

iScience
Myint ZM, Koide Y, Takanishi W, Ikegaya T, Kwan C, Hikichi K, Tokuyama Y, Okada S, Onishi K, Ishikawa R, Fujita D, Yamagata Y, Matsumura H, Kishima Y, Kanazawa A.   +14 more
europepmc   +1 more source

Oral Recombinant Human Collagen III Protects Gastric Mucosa via G‐Quadruplex‐Mediated Activation of the Pla2g4a‐Prostaglandin Axis

Advanced Science, EarlyView.
Orally administered recombinant human type III collagen protects the gastric mucosa from ethanol‐induced injury by coordinating redox homeostasis, epithelial barrier repair, and arachidonic acid–prostaglandin metabolism. Gastric digestion releases the pentapeptide GPAEF, which interacts with the Pla2g4a promoter G‐quadruplex in a structure‐dependent ...
Xinyue Lan, Qiu Dai, Yanhui Wang, Jiaxuan Gu, Chengyun Wang, Weicheng Xu, Xinru Gao, Jiageng Cheng, Wentao Geng, Xiaowen Wu, Haihang Li, Xiaoyun He, Shengwei Fu, Longjiao Zhu, Wentao Xu   +14 more
wiley   +1 more source

Hybrid Sterility in Fish Caused by Mitotic Arrest of Primordial Germ Cells. [PDF]

Genetics, 2018
Yoshikawa H, Xu D, Ino Y, Yoshino T, Hayashida T, Wang J, Yazawa R, Yoshizaki G, Takeuchi Y.   +8 more
europepmc   +1 more source