Uterine Rupture on Invasive Molar Pregnancy Revealing a Choriocarcinoma: Case Report from a Low-Income Country. [PDF]
Introduction Gestational trophoblastic diseases are rare entities encompassing a wide spectrum of benign and malignant placental pathologies. Uterine rupture is primarily related to a uterine scar and, exceptionally, following an invasive mole or gestational choriocarcinoma.
Zoly RN +4 more
europepmc +2 more sources
Therapeutic approach to the iatrogenic invasive mole: A report of two cases [PDF]
Introduction. Invasive mole, a form of gestational trophoblastic neoplasia (GTN), is defined as penetration of molar tissue into the myometrium and/or presence of extra-uterine metastases.
Rakić Aleksandar +3 more
doaj +1 more source
Invasive hydatidiform mole in a perimenopausal woman
Shi-Ping Lu, Bi-Fei Huang, Chao-Qun Wang
doaj +3 more sources
Gestational trophoblastic disease a contemporary review of diagnostic and pathology. Current challenge and future directions for gynecologists and obstetricians [PDF]
Gestational trophoblastic disease (GTD) is a heterogenous group of disorders assosiated with abnromal proliferation of trophoblast and their course is characterized by varying degrees of malignancy.
Hanna Senat +5 more
doaj +3 more sources
Laparoscopic management of an invasive mole combined with iatrogenic uterine perforation
Objective: Hydatidiform mole is a common placental proliferative disease which is harmful to women's reproductive health. It is characterized by abnormal fertilization and subsequent trophoblastic proliferation. Invasive mole originates from hydatidiform
Qiaoying Jiang +3 more
doaj +1 more source
Whole-genome paternal uniparental disomy identified through prenatal single-nucleotide polymorphism-based cell-free DNA screening. [PDF]
ABSTRACT Objective Prenatal single‐nucleotide polymorphism (SNP)‐based cell‐free DNA (cfDNA) screening can identify genome‐wide paternal uniparental disomy (GW‐UPDpat), including cases with complete hydatidiform mole with a coexisting fetus (CHMCF), those with placental mesenchymal dysplasia (PMD) and those with a mosaic/chimeric GW‐UPDpat syndrome ...
Benn P +5 more
europepmc +2 more sources
A Rare Case of Choriocarcinoma With Myometrial Invasion Mimicking Invasive Mole: Case Report. [PDF]
ABSTRACT Gestational trophoblastic neoplasia (GTN) comprises a group of rare tumors arising from placental trophoblastic tissue, including choriocarcinoma and invasive mole. We present a rare case of choriocarcinoma with isolated myometrial invasion in a 30‐year‐old woman with a history of molar pregnancy and term delivery.
Vandadi S +4 more
europepmc +2 more sources
GESTATIONAL TROPHOBLASTIC DISEASE IN BASRAH [PDF]
To date few studies have been reported from Basrah regarding Gestational Trophoblastic disease GTD. This study was a clinical observational study done in Basrah at the 4 main obstetric hospitals based on 137 patients with GTD.
Hassna M. Chaied, Zaineb .T. AL Yasin
doaj +1 more source
Downregulation of Chromosome 19 miRNA Cluster and the Tumor-Suppressive Role of miR-517a-3p in Choriocarcinoma. [PDF]
Chromosome 19 microRNA cluster was downregulated in choriocarcinoma compared with complete hydatidiform mole. miR‐517a‐3p reduced the proliferation, migration, and invasion abilities of choriocarcinoma cell lines. Downregulation of SRSF1, targeted by miR‐517a‐3p, suppressed the malignant potential of choriocarcinoma cell lines. ABSTRACT Choriocarcinoma
Nishiko Y +14 more
europepmc +2 more sources
A rare cause of postpartum vaginal bleeding
Background Invasive mole is a trophoblastic disease (GTD) caused by trophoblast cells invading the myometrium during pregnancy. The GTD range also includes mole hydatidiform, choriocarcinoma, and placental site trophoblastic tumor (PSTT).
Oğuzhan Tokur +3 more
doaj +1 more source

