Results 71 to 80 of about 2,351 (219)

Mechanisms of matrix metalloproteinase-2 (mmp-2) transcriptional repression by progesterone in jar choriocarcinoma cells [PDF]

, 2009
Background Although the MMP-2 promoter lacks a canonical progesterone response element (PRE), the hormone inhibits MMP-2 expression and is part of treatment protocols in gynecological invasive pathologies, including endometriosis and endometrial ...
Shlomit Goldman, David H Lovett, Eliezer Shalev   +2 more
core   +2 more sources

Termination of twin pregnancies with hydatidiform moles: a case series of four patients.

Iranian Journal of Public Health, 2014
P A twin pregnancy with a complete hydatidiform mole with a coexistent foetus (CHMF) is a rare condition that typically results in poor pregnancy outcomes.
Mei Peng, Li Li, Jingjie Zheng, Yiling Ding, Ling Yu, Jian Huang   +5 more
doaj  

Integrating High-intensity Focused Ultrasound with Chemotherapy for the Treatment of Invasive Hydatidiform Mole in Reproductive-age Women

Gynecology and Minimally Invasive Therapy
Invasive hydatidiform mole, a form of gestational trophoblastic neoplasm in reproductive-age women, poses a significant threat to life due to its associated signs and symptoms.
Yongmiao Pan, Kaiqing Lin, Ying Hu, Xiaohong Song, Linjun Xu, Zhenfeng Zhou, Di Xie, Yuan Xue   +7 more
doaj   +1 more source

Study of gestational trophoblastic diseases at a tertiary care hospital in India [PDF]

, 2018
Background: Gestational trophoblastic disease refers to the heterogeneous group of interrelated lesions that arises from abnormal proliferation of placental trophoblasts.
Antaratani, Ramalingappa C., M., Shruthi
core   +2 more sources

Diagnosis and management of gestational trophoblastic disease: 2025 update

International Journal of Gynecology &Obstetrics, Volume 171, Issue S1, Page 78-86, September 2025.
Abstract Gestational trophoblastic disease (GTD) arises from abnormal placenta and comprises a spectrum of premalignant to malignant disorders. Changes in the epidemiology of GTD have been noted in various countries. In addition to histology, molecular genetic studies can help in the diagnostic pathway.
Hextan Y. S. Ngan, Michael J. Seckl, Ross S. Berkowitz, Yang Xiang, François Golfier, Paradan K. Sekharan, Antonio Braga, Andrea Garrett   +7 more
wiley   +1 more source

Molar Tissue in Spleen: A Case Report

Middle East Journal of Cancer, 2016
An invasive mole is a rare form of gestational trophoblastic disease in which the molar tissue invades into the deep myometrium, cervical stroma, blood vessels or extrauterine sites. This report is of an invasive mole of spleen that has originated from
Maral Mokhtari, Mojgan Akbarzadeh Jahromi, Zeinab Amiri, Mozhdeh Momtahan   +3 more
doaj  

Molecular and immunohistochemical characteristics of complete hydatidiform moles

Balkan Journal of Medical Genetics, 2017
Molar pregnancy is a gestational trophoblastic disease that belongs to the category of precancerous lesions. On the other end of the spectrum are gestational trophoblastic neoplasms such as invasive mole, choriocarcinoma, placental site trophoblastic ...
Kubelka-Sabit KB, Prodanova I, Jasar D, Bozinovski G, Filipovski V, Drakulevski S, Plaseska-Karanfilska D   +6 more
doaj   +1 more source

Gestational Trophoblastic Neoplasia in the 1990s [PDF]

, 2013
Major advances have been achieved during the past 40 years in the epidemiology, etiology, pathology, endocrinology, immunology, diagnosis, and treatment of molar pregnancy (MP) and gestational trophoblastic neoplasia (GTN).
Goldstein, Donald Peter
core  

ENT‐1‐Targeted Polymersomes to Enhance the Efficacy of Methotrexate in Choriocarcinoma Treatment

Small Science, Volume 5, Issue 7, July 2025.
ENT‐1‐targeted stimuli‐responsive polymersomes enhance the delivery and release of MTX, as demonstrated in choriocarcinoma tumors mouse model. These targeted nanocarriers improve tumor uptake and efficiently release the drug within the tumor, highlighting their potential for enhanced chemotherapy in choriocarcinoma treatment.
Babak Mamnoon, Ana Paula Mesquita Souza, Tetiana Korzun, Maureen K. Baldwin, K. Shitaljit Sharma, Oleh Taratula, Yoon Tae Goo, Prem Singh, Vladislav Grigoriev, Aryan Lakhanpal, Olena R. Taratula   +10 more
wiley   +1 more source

Placental site trophoblastic disease in practice of gynecologist (case report). [PDF]

Гинекология
Gestational trophoblastic disease is uncommon in practice. Usually a hydatidiform mole, an invasive mole and a choriocarcinoma are known among gynecologists.
Igor E. Fadeev, Tatiana N. Sotnikova, Еvgenii A. Bruzgin, Tatiana N. Poletova, Tatiana V. Polushkina   +4 more
doaj   +1 more source