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The hydatidiform mole [PDF]

open access: yesCell Adhesion and Migration, 2016
The hydatidiform mole (HM) is a placental pathology of androgenetic origin. Placental villi have an abnormal hyperproliferation event and hydropic degeneration. Three situations can be envisaged at its origin: 1. The destruction/expulsion of the female pronucleus at the time of fertilization by 1 or 2 spermatozoa with the former being followed by an ...
Jean-Jacques Candelier
exaly   +3 more sources

Tubal hydatidiform mole

American Journal of Obstetrics and Gynecology, 1993
We report a tubal hydatidiform mole, most likely resulting from dispermic fertilization. Early hatching of the embryo, because of a defective zona pellucida, may have favored tubal implantation.
M Coppens, M Dhont, Marc Dhont
exaly   +3 more sources

The Thyrotoxicosis of Hydatidiform Mole

Annals of Internal Medicine, 1975
In 14 women with hydatidiform mole, 9 were hyperthyroid. Serum thyroxine (T4) levels varied between 18 and 34 mug/100 ml, and serum triiodothyronine (T3) levels between 300 and 800 ng/100 ml in the hyperthyroid patients. Bioassayable thyroid-stimulating hormone (molar TSH) was found in high concentrations in the serum of 13 patients in whom ...
H P, Higgins   +5 more
openaire   +2 more sources

Immunogenicity of hydatidiform mole

Placenta, 1987
The HLA and ABO systems were studied in patients with complete hydatidiform mole (CHM). The study confirmed that CHM can immunize the patient against paternally derived HLA-ABC antigens. In patients who required subsequent treatment for trophoblastic tumours the frequency of antibody detection was much higher (10/14) at the time of treatment than it ...
S D, Lawler, R A, Fisher
openaire   +2 more sources

STEROIDS OF HYDATIDIFORM MOLES

Journal of Endocrinology, 1968
Abstract This communication reports on a comparison of the steroids of normal placentae (see Chamberlain, Morris & Smith, 1968) and of three hydatidiform moles. All three cases of hydatidiform mole showed the fairly typical gross changes associated with this condition and histological examination confirmed the diagnosis.
J, Chamberlain, N F, Morris, N C, Smith
openaire   +2 more sources

Recurrent hydatidiform moles

European Journal of Obstetrics & Gynecology and Reproductive Biology, 2010
Hydatidiform moles (HMs) are abnormal conceptions of excessive trophoblast development resulting in abnormal human pregnancies with no embryo and cystic degeneration of the chorionic villi. Prompt diagnosis, treatment and follow-up of patients using assays for betahCG from centres that specialise in this condition enable early diagnosis of potential ...
Denise, Williams   +2 more
openaire   +2 more sources

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