Results 61 to 70 of about 3,909 (174)

Expression of Pro-Apoptotic Bax and Anti-Apoptotic Bcl-2 Proteins in Hydatidiform Moles and Placentas With Hydropic Changes

Acta Medica Iranica, 2019
Morphologic examination still forms the main diagnostic tool in the differential diagnosis of molar placentas. However the criteria are subjective and show considerable inter-observer variability among pathologists.
Alireza Khooei, Fatemeh Atabaki Pasdar, Alireza Fazel, Mahmoud Mahmoudi, Mohammad Reza Nikravesh, Shahin Daneshmand Shahbazian   +5 more
doaj  

Downregulation of Chromosome 19 miRNA Cluster and the Tumor‐Suppressive Role of miR‐517a‐3p in Choriocarcinoma

Cancer Science, Volume 116, Issue 12, Page 3473-3486, December 2025.
Chromosome 19 microRNA cluster was downregulated in choriocarcinoma compared with complete hydatidiform mole. miR‐517a‐3p reduced the proliferation, migration, and invasion abilities of choriocarcinoma cell lines. Downregulation of SRSF1, targeted by miR‐517a‐3p, suppressed the malignant potential of choriocarcinoma cell lines. ABSTRACT Choriocarcinoma
Yuki Nishiko, Kosuke Yoshida, Yuko Yasui, Akira Yokoi, Masami Kitagawa, Eri Inami, Masato Yoshihara, Kazumasa Mogi, Yukari Nagao, Satoshi Tamauchi, Nobuhisa Yoshikawa, Kimihiro Nishino, Eiko Yamamoto, Kaoru Niimi, Hiroaki Kajiyama   +14 more
wiley   +1 more source

Six New Cases of 22q13.2 Gain Including TFC20: First Report of Triplication and Smallest Duplication Associated With Neurodevelopmental Delays

Clinical Genetics, Volume 108, Issue 6, Page 731-741, December 2025.
This study reports six new cases of 22q13.2 duplication and triplication, including the TCF20 gene, associated with neurodevelopmental disorders and various morphological and systemic abnormalities. The findings suggest a variable expressivity, but their complete penetrance remains uncertain compared to well‐established loss‐of‐function variants ...
Etienne Bizot, Dima Jouni, Caroline Rooryck, Juliet Taylor, Marine Legendre, Lorelei Charbonnier, Julia Metreau, Emmanuelle Benaloun, Audrey Pinson, Geneviève Quenum, Jérôme Bouligand, Gérard Tachdjian, Philippe Labrune, Lucie Tosca   +13 more
wiley   +1 more source

Trend of Complete Hydatidiform Mole

Journal of Nepal Medical Association, 2010
INTRODUCTION: Complete Hydatidiform mole is one of the most frequent abnormal pregnancies. This review studies the trend of complete mole in Paropakar Maternity and Women's hospital and clinical ability to detect it.
K Thapa, M Shrestha, S Sharma, S Pandey
doaj   +1 more source

Gestational trophoblastic neoplasia with pulmonary embolism mimicking tuberculosis

Journal of Family Medicine and Primary Care
Gestational trophoblastic neoplasia (GTN) comprises a group of human neoplastic diseases that derive from fetal trophoblastic tissues. They are proliferative as well as degenerative disorders of placental elements and include complete hydatidiform mole ...
Varuna Jethani, Sushant Khanduri, Ankit Batra, Shivam Sinha   +3 more
doaj   +1 more source

P53 expression in various types of hydropic placentas (through ploidy analysis as a complementary tool in diagnosis of samples)

Caspian Journal of Internal Medicine, 2019
Background: Placentas characterized by hydropic swelling of chorionic villi occur in a spectrum of pathological conditions including hydropic abortion (HA), partial hydatidiform mole (PHM) and complete hydatidiform mole (CHM).
Alireza Khooei, Fatemeh Atabaki Pasdar, Alireza Fazel, Mahmoud Mahmoudi, Mohammad Reza Nikravesh, shahrzad Daneshmand Shahbazian   +5 more
doaj  

Gestational Trophoblastic Disease: Complete versus Partial Hydatidiform Moles

Diseases
Hydatidiform moles, including both complete and partial moles, constitute a subset of gestational trophoblastic diseases characterized by abnormal fertilization resulting in villous hydrops and trophoblastic hyperplasia with or without embryonic ...
Jeffrey Gonzalez, Meagan Popp, Stephanie Ocejo, Alvaro Abreu, Hisham F. Bahmad, Robert Poppiti   +5 more
doaj   +1 more source

Thyrotoxicosis in pregnancy: A case report

Sultan Qaboos University Medical Journal, 2001
There are various causes of hyperthyroidism in pregnancy such as Graves’ disease and gestational thyrotoxicosis. The thyroid stimulation results from the excessive levels of circulating human chorionic gonadotropin (hCG) produced by the trophoblastic ...
Bola R Kamath, Kamla J Rao, Adikari AK Mayadunne   +2 more
doaj  

Hydatidiform Mole

Transactions. Edinburgh Obstetrical Society
Cue L, Farci F, Ghassemzadeh S, Kang M.
europepmc   +2 more sources

Giant complete hydatidiform mole: a case report and review of the literature

Journal of Medical Case Reports
Background This case describes the youngest patient documented in the literature who presented with a giant hydatidiform mole, effectively addressed through conservative treatment. Case presentation Our department received a 20-year-old Caucasian patient
Iris Bonomo, Suzy Fopa, Grégory Van Vinckenroy, Charlotte Maillard   +3 more
doaj   +1 more source