Results 11 to 20 of about 21,944 (215)

HYpofractionated, dose-redistributed RAdiotherapy (HYDRA) versus conventional radiotherapy for head and neck cancer: planned interim analysis and dosimetric comparison from the phase I HYDRA trial [PDF]

open access: yesClinical and Translational Radiation Oncology
Purpose: (Chemo)radiotherapy for squamous cell carcinoma of the oropharynx, hypopharynx, and larynx results in significant treatment burden and may cause radiation-induced lymphopenia (RIL), which is associated with worse survival.
Pascal A. Gunsch   +10 more
doaj   +2 more sources

Interpretable deep generative ensemble learning for single-cell omics with Hydra [PDF]

open access: yesMolecular Systems Biology
Single-cell omics enable the dissection of cellular heterogeneity, yet the high dimensionality, inherent noise, and sparsity present significant challenges.
Manoj M Wagle   +6 more
doaj   +2 more sources

Species-Specific Viromes in the Ancestral Holobiont Hydra [PDF]

open access: yesPLoS ONE, 2014
Recent evidence showing host specificity of colonizing bacteria supports the view that multicellular organisms are holobionts comprised of the macroscopic host in synergistic interdependence with a heterogeneous and host-specific microbial community ...
Soren Franzenburg   +2 more
exaly   +2 more sources

Wnt signaling restores evolutionary loss of robust foot regeneration rates in Hydra [PDF]

open access: yesNature Communications
The regenerative potential of animals varies widely, even among closely related species. In a comparative study of regeneration across the Hydra genus, we found that while most species exhibit robust whole-body regeneration, Hydra oligactis and other ...
Sergio E. Campos   +9 more
doaj   +2 more sources

PETRI NETS MODELING FOR SDN TOPOLOGIES [PDF]

open access: yesJournal of Engineering Science (Chişinău), 2021
The article examines some new algorithms and focuses mainly on suggesting new working topologies for software-defined controllers in order to ensure SDN security and to prevent the occurrence of a potential central point of failure (SPOF) by overcoming ...
AMEEN, Ali, GUȚULEAC, Emilian
doaj   +1 more source

Half-Life of Biodegradable Plastics in the Marine Environment Depends on Material, Habitat, and Climate Zone

open access: yesFrontiers in Marine Science, 2021
The performance of the biodegradable plastic materials polyhydroxybutyrate (PHB), polybutylene sebacate (PBSe) and polybutylene sebacate co-terephthalate (PBSeT), and of polyethylene (LDPE) was assessed under marine environmental conditions in a three ...
Christian Lott   +8 more
doaj   +1 more source

State of the Art Offshore In Situ Monitoring of Microplastic

open access: yesMicroplastics, 2022
Microplastics make up a significant amount of the overall quantity of plastic debris that is present in seawater. However, their detection and monitoring at sea is cost-inefficient and challenging; typically, it consists of water sampling with special ...
Daniele Calore, Nicola Fraticelli
doaj   +1 more source

Ecotoxicological Tools to Assess Cytostatic Effects in Freshwater Environments: Aiding Drug Prioritization

open access: yesMedical Sciences Forum, 2022
Given the growing number of cancer diseases, new cytostatic drugs are approved daily, often with concomitant development, or refinement of some of these drugs aimed at decreasing patient discomfort during the administration period (e.g., prodrugs ...
Cátia Venâncio   +6 more
doaj   +1 more source

Transforming Life Science Through Chromosome-Level Genome Assemblies. [PDF]

open access: yesGenes Cells
Chromosome‐level genome assemblies provide a framework for “glocal biology” in species of interest, linking local molecular features to chromosome architecture and evolutionary context. When integrated with pangenome analysis, comparative multi‐omics, genome language models, and experimental approaches, these assemblies enable hypothesis generation and
Kon T   +7 more
europepmc   +2 more sources

Conservation of the nucleotide excision repair pathway: characterization of hydra Xeroderma Pigmentosum group F homolog. [PDF]

open access: yesPLoS ONE, 2013
Hydra, one of the earliest metazoans with tissue grade organization and nervous system, is an animal with a remarkable regeneration capacity and shows no signs of organismal aging.
Apurva Barve   +2 more
doaj   +1 more source

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