Results 141 to 150 of about 3,191,259 (277)

Immobilization of Alginate Microbeads With Whole‐Cells Expressing Nitrilase for Continuous Nicotinic Acid Production in Chip Millireactor

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The biocatalytic production of nicotinic acid using nitrilases has emerged as a promising alternative to conventional chemical synthesis, offering improved selectivity and environmental sustainability. In this study, we developed a continuous‐flow millireactor system employing Escherichia coli cells expressing a nitrilase from Paraburkholderia
Jonathan Bassut, Emina Mehić, Luana Cuvillier, Carine Vergne‐Vaxelaire, Jean‐Louis Petit, Maïté Michaud, Zoé Anxionnaz‐Minvielle, Anne Zaparucha, Guillaume Nonglaton   +8 more
wiley   +1 more source

Serotype‐Tailored Midstream and Downstream Operations to Advance the Manufacturing of Adeno‐Associated Viral Vectors

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Adeno‐associated viruses (AAVs) are the leading vectors for in vivo gene therapy, fueling a growing demand for scalable and robust biomanufacturing processes. Yet, the impact of cell lysis conditions on the performance of midstream and downstream unit operations across serotypes remains poorly characterized.
Arianna Minzoni, Shriarjun Shastry, Eduardo Barbieri, Morgan R. Hurst, Kelvin Idanwekhai, Yuxuan Wu, Katherine Ernst, Wai‐Keen Chung, Christopher Bombeck, Saad A. Khan, Sushmita Koley, Gabriella Kiss, Oliver Rammo, Alexander Tropsha, Cristiana Boi, Michael A. Daniele, Steven Cramer, Barry Byrne, Stephen Kaminsky, Angie Snell Bennett, Stefano Menegatti   +20 more
wiley   +1 more source

Bale Core Operating Device

, 1918
Patent for bale core operating device which improves the bale core quality around which the bale is formed, including ...
Taft, John A.
core  

Medical device-related pressure injuries in the operating room: A scoping review

Aims To map the existing literature describing medical device-related pressure injuries in patients during surgery, including investigation of the incidence, types of medical devices, risk factors and strategies for preventing medical device-related ...
Kuruppu, Nipuna Randini, Tobiano, Georgia, Lee, Bih-O, Gillespie, Brigid M, Ou, Su Fei, Huang, Tai-Yang   +5 more
core   +1 more source

A Microfluidic TFF Device for Biopharmaceutical Process Development: Scale‐Down Verification of Ultrafiltration and Diafiltration Modes for Monoclonal Antibodies

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Tangential flow filtration (TFF) is an essential operation in downstream bioprocessing, yet conventional scale‐down models require large material volumes and often fail to capture scale‐relevant hydrodynamics. A microfluidic TFF (µTFF) platform was developed that preserves wall shear rate and transmembrane pressure, enabling low‐volume ...
Nusrat Jahan, Nicolas Szita, Spyridon Konstantinidis, Marco P. C. Marques   +3 more
wiley   +1 more source

British Hydraulic Engineering and Research

, 1963
Overview of hydraulic research in the United Kingdom in the period before 1963.Hydraulic EngineeringCivil Engineering and ...
Allen, J. (author)
core  

From muscle fibres to muscle gears: how dynamic fascicle orientation and shape change impact skeletal muscle function

Biological Reviews, EarlyView.
ABSTRACT Skeletal muscle architectural design strongly affects force‐generating capacity and excursion range, and its functional importance to animal and human movement is well founded. Traditionally, this ‘structure–function relation’ has been inferred from architecture measurements with muscles at rest (from anatomical dissections or medical imaging ...
Matheus D. Pinto, James M. Wakeling, Javier A. Almonacid, Anthony J. Blazevich   +3 more
wiley   +1 more source

Elucidating the Interplay Between Structure and Electrochemical Behavior in Lignin‐Based Polymer Electrolytes for Potassium Batteries

Battery Energy, Volume 4, Issue 2, March 2025.
Three biobased membranes are synthesized by crosslinking oxidized Kraft lignin with poly(ethylene glycol) diglycidyl ether of increasing molecular weights. After incorporation of solvated potassium salts, potassium batteries including these biobased gel polymer electrolytes are able to deliver a maximum specific capacity at 0.05 A g−1 as high as 130 ...
Giuseppe Pascuzzi, Sabrina Trano, Carlotta Francia, Stefano Turri, Federico Bella, Gianmarco Griffini   +5 more
wiley   +1 more source

CO-Simulation Analysis of Hydraulic Steel-Belt Overwind Buffer Device

, 2013
: In this study, we obtain overwind buffer distance by using the Lagrange equation to establish the twodegrees-of-freedom mathematical model with vertical shaft lifting system in rolling process. Design of a buffer device which is composed of a hydraulic
Wu Juan, Kou Ziming
core  

Review of CFD modelling techniques for single‐phase and multiphase flow in static mixers

The Canadian Journal of Chemical Engineering, EarlyView.
This review synthesizes computational fluid dynamics (CFD) approaches for static mixers, linking hydrodynamics to pressure drop, particle/droplet distributions, mixing metrics, and heat‐transfer performance to guide modelling choices and design decisions. Abstract Static mixers enable compact and low‐energy intensification.
Jussan Jaeger, Sálvio Lima de Carvalho Neto, Silvio Edegar Weschenfelder, Glaucia Rodrigues Vieira de Almeida da Fonseca, Maria de Fátima Rodrigues da Cunha, Selene Maria Arruda Guelli Ulson de Souza, Evandro Balestrin, Adriano da Silva   +7 more
wiley   +1 more source