Results 231 to 240 of about 733,326 (334)

Development of Dimethylsulfonium Probes for Broad Profiling of Methyllysine Reader Proteins

open access: yesAdvanced Science, EarlyView.
Development of oligoglycine‐based dimethylsulfonium probes for unbiased crosslinking to methyllysine readers. The general probe facilitates profiling of site‐specific methyllysine readers, evaluation of selectivity and activity of reader inhibitors, and global profiling of methyllysine readers.
Jinyu Yang   +3 more
wiley   +1 more source

Microwave Ultrafast Heating on Iron‐based Nanogap Catalysts for CO2 Reduction Coupling with Coke Removal

open access: yesAdvanced Science, EarlyView.
This study employs a nanogap‐induced microwave discharge strategy to pretreat coke deposits on iron‐based catalysts with engineered nanogaps, causing ultrarapid heating to 1990 K within seconds, selectively eliminating >70% surface carbon deposits and converting waste plastics and greenhouse gases into syngas.
Xi Shen   +4 more
wiley   +1 more source

Phocaeicola coprophilus‐Derived 6‐Methyluracil Attenuates Radiation‐Induced Intestinal Fibrosis by Suppressing the IDO1‐Kynurenine‐AHR Axis

open access: yesAdvanced Science, EarlyView.
IR‐induced dysbiosis depletes P. coprophilus and its metabolite 6‐methyluracil, leading to disinhibition of the IDO1‐Kyn‐AHR axis. This results in sustained fibroblast activation and collagen deposition, driving radiation induced intestinal fibrosis. ABSTRACT Therapeutic options for radiation‐induced intestinal fibrosis (RIF) remain limited. This study
Jiaxin Zhang   +11 more
wiley   +1 more source

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