Monro-Kellie 2.0: The dynamic vascular and venous pathophysiological components of intracranial pressure [PDF]
For 200 years, the ‘closed box’ analogy of intracranial pressure (ICP) has underpinned neurosurgery and neuro-critical care. Cushing conceptualised the Monro-Kellie doctrine stating that a change in blood, brain or CSF volume resulted in reciprocal ...
Wilson, MH
core +1 more source
Precision therapies for genetic epilepsies in 2025: Promises and pitfalls
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang +3 more
wiley +1 more source
Imaging diagnosis: magnetic resonance imaging of diffuse leptomeningeal oligodendrogliomatosis in a dog with "dural tail sign" [PDF]
A case of diffuse leptomeningeal oligodendrogliomatosis affecting the brain and spinal cord of a dog is presented. A 7.5-year old, male neutered Staffordshire bull terrier presented for evaluation of a chronic history of tetraparesis and seizures, with a
Anwer +31 more
core +1 more source
Enhancing spatial cognition through origami training: Insights from brain connectomes
Origami training enhances spatial cognition via measurable brain network changes (EEG/eye‐tracking). The mental rotation and folding tasks validate these gains. This low‐cost method offers a scalable intervention for cognitive decline. Abstract Spatial cognition is a key ability of human cognition and intelligence.
Xiuyun Liu +13 more
wiley +1 more source
Hakim-Adams syndrome: An unusual cause of reversible postoperative coma.
We report the case of a 72 years old patient presenting in our ICU with persistent postoperative coma in a context of recent unexplored neurological dysfunction. Detailed medical history taking from the patient’s family revealed he recently suffered from
Mohamed SALEH, Marine Bouex
doaj +1 more source
Barriers to nutrition following neurosurgery: A descriptive cohort study
Abstract Background Neurological trauma results in a state of hypermetabolism. Existing literature has explored barriers to adequate nutrition following traumatic brain injury. Despite clinical similarities, it remains unclear whether similar nutritional barriers are faced following both planned and emergency neurosurgical procedures.
Dale Palmer, Melissa Zhou, Suzie Ferrie
wiley +1 more source
Neuroimaging in normal pressure hydrocephalus
Normal pressure hydrocephalus (NPH) is a syndrome characterized by the triad of gait disturbance, mental deterioration and urinary incontinence, associated with ventriculomegaly and normal cerebrospinal fluid (CSF) pressure.
Benito Pereira Damasceno
doaj +1 more source
A Closer Look at the Global Management of Spina Bifida: The Implementation of Endoscopic Third Ventriculostomy in the Treatment of Spina Bifida-Related Hydrocephalus in Africa [PDF]
Spina bifida, specifically myelomeningocele, is a debilitating neural tube defect that affects patients and families throughout the world. Traditional management and treatment methods are described, followed by an explanation of why this is often ...
Burckart, Caryssa
core +1 more source
Purpose To investigate the pathological change of the glymphatic system in idiopathic normal pressure hydrocephalus (iNPH) using diffusion tensor imaging (DTI) analysis.
H. Yokota +7 more
semanticscholar +1 more source
Junctional adhesion molecule (JAM)-C deficient C57BL/6 mice develop a severe hydrocephalus [PDF]
The junctional adhesion molecule (JAM)-C is a widely expressed adhesion molecule regulating cell adhesion, cell polarity and inflammation. JAM-C expression and function in the central nervous system (CNS) has been poorly characterized to date.
Adams, Ralf Heinrich +10 more
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