Results 281 to 290 of about 199,619 (340)

Predicting hospice eligibility among dementia patients using language models

Alzheimer's &Dementia, Volume 21, Issue 11, November 2025.
Abstract INTRODUCTION Alzheimer's disease and related dementias (ADRD) are increasing in prevalence, and access to potential benefits of hospice care remains challenging. Large language models (LLMs), like GPT‐4o, applied to electronic health records (EHRs) could support decisions by estimating mortality risk.
Thomas H. McCoy, Roy H. Perlis
wiley   +1 more source

Communicating Hydrocephalus After Radiotherapy for a Vestibular Schwannoma. [PDF]

Cureus
Set HHM, Sann KN, Shanmugasundaram R.
europepmc   +1 more source

Blood‐based Alzheimer's disease biomarkers in a behavioral neurology clinic: Real‐world implementation, clinical utility, and diagnostic performance

Alzheimer's &Dementia, Volume 21, Issue 11, November 2025.
Abstract INTRODUCTION Blood‐based biomarkers (BBMs) for Alzheimer's disease (AD), including plasma phosphorylated tau (p‐tau), are increasingly used in clinical practice, but “real‐world” implementation patterns, context‐of‐use (COU), clinical utility, and diagnostic performance are incompletely understood. METHODS A retrospective analysis of the first
Igor Prufer Q C Araujo, Tara Ellingson, Nicholas U. Schwartz, Connor D. Dietz, Gautam Tammewar, Kaancan Deniz, Manizhe Eslami‐Amirabadi, Andrew G. Breithaupt, Marci Rosenberg, Nhat Minh Bui, Yasmeen Gonzalez, Renaud La Joie, Peter A. Ljubenkov, Katherine L. Possin, Julio C. Rojas, David N. Soleimani‐Meigooni, Yingbing Wang, Adam M. Staffaroni, Melanie L. Stephens, Elena Tsoy, Charles C. Windon, Adam L. Boxer, Gil D. Rabinovici, Bruce L. Miller, Lawren VandeVrede   +24 more
wiley   +1 more source

Mutations in the Key Autophagy Tethering Factor EPG5 Link Neurodevelopmental and Neurodegenerative Disorders Including Early‐Onset Parkinsonism

Annals of Neurology, Volume 98, Issue 5, Page 932-950, November 2025.
Objective Autophagy is a fundamental biological pathway with vital roles in intracellular homeostasis. During autophagy, defective cargoes including mitochondria are targeted to lysosomes for clearance and recycling. Recessive truncating variants in the autophagy gene EPG5 have been associated with Vici syndrome, a severe early‐onset neurodevelopmental
Hormos Salimi Dafsari, Celine Deneubourg, Kritarth Singh, Reza Maroofian, Zita Suprenant, Ay Lin Kho, Neil J Ingham, Karen P Steel, Preethi Sheshadri, Franciska Baur, Lea Hentrich, Birgit Gerisch, Mina Zamani, Cesar Alves, Ata Siddiqui, Haidar S Dafsari, Mehri Salari, Anthony E. Lang, Michael Harris, Alice Abdelaleem, Saeid Sadeghian, Reza Azizimalamiri, Hamid Galehdari, Gholamreza Shariati, Alireza Sedaghat, Jawaher Zeighami, Daniel Calame, Dana Marafi, Ruizhi Duan, Adrian Boehnke, Gary D. Clark, Jill A. Rosenfeld, Carrie A. Mohila, Dora Steel, Saurabh Chopra, Suvasini Sharma, Nicolai Kohlschmidt, Steffi Patzer, Afshin Saffari, Darius Ebrahimi‐Fakhari, Büşra Eser Çavdartepe, Irene J Chang, Erika Beckman, Renate Peters, Andrew Paul Fennell, Bernice Lo, Luisa Averdunk, Felix Distelmaier, Martina Baethmann, Frances Elmslie, Kairit Joost, Sheela Nampoothiri, Dhanya Yesodharan, Hanna Mandel, Amy Kimball, Antonie D. Kline, Cyril Mignot, Boris Keren, Vincent Laugel, Katrin Õunap, Kalpana Devadathan, Frederique M.C. van Berkestijn, Arpana Silwal, Saskia Koene, Sumit Verma, Mohammed Yousuf Karim, Chahynez Boubidi, Majid Aziz, Gehad ElGhazali, Lauren Mattas, Mohammad Miryounesi, Farzad Hashemi‐Gorji, Shahryar Alavi, Nayereh Nouri, Mehrdad Noruzinia, Saeideh Kavousi, Arveen Kamath, Sandeep Jayawant, Russell Saneto, Nourelhoda A. Haridy, Pinar Ozkan Kart, Ali Cansu, Madeleine Joubert, Claire Beneteau, Kyra E. Stuurman, Martina Wilke, Tahsin Stefan Barakat, Homa Tajsharghi, Annarita Scardamaglia, Sadeq Vallian, Semra Hız, Ali Shoeibi, Reza Boostani, Narges Hashemi, Meisam Babaei, Norah Saleh Alsaleh, Julie Porter, Tania Attié‐Bitach, Pauline Marzin, Dorota Wicher, Jessica I. Gold, Elisabeth Schuler, Amna Kashgari, Rakan F. Alanazi, Wafaa Eyaid, Marc Engelen, Mirjam Langeveld, Burkhard Stüve, Yun Li, Gökhan Yigit, Bernd Wollnik, Mariana H.G Monje, Dimitri Krainc, Niccolò E. Mencacci, Somayeh Bakhtiari, Michael Kruer, Emanuela Argilli, Elliott Sherr, Yalda Jamshidi, Ehsan Ghayoor Karimiani, Yiu Wing Sunny Cheung, Ivan Karin, Giovanni Zifarelli, Peter Bauer, Wendy K Chung, James R. Lupski, Manju A. Kurian, Jörg Dötsch, Jürgen‐Christoph von Kleist‐Retzow, Thomas Klopstock, Matias Wagner, Calvin Yip, Andreas Roos, Rita Carsetti, Carlo Dionisi‐Vici, Mathias Gautel, Michael R Duchen, Adam Antebi, Henry Houlden, Manolis Fanto, Heinz Jungbluth   +140 more
wiley   +1 more source

Is there an optimal sequencing of endoscopic third ventriculostomy and stereotactic radiosurgery for brain metastasis with secondary obstructive hydrocephalus? Illustrative case. [PDF]

J Neurosurg Case Lessons
Goulenko V, Madhugiri VS, Almeida ND, Shekher R, Fabiano AJ, Prasad D.   +5 more
europepmc   +1 more source

A case of normal pressure hydrocephalus presenting as repeated vertigo, headache and nausea and treated effectively with ventriculoparietal shunt surgery

, 2009
Shinichi Iwasaki, Yasuhiro Chihara, Munetaka Ushio, Keiko Sugasawa, Mitsuya Suzuki, Tatsuya Yamasoba, Toshihisa Murofushi   +6 more
openalex   +2 more sources

Taking Down the Primary Cilium: Pathways for Disassembly in Differentiating Cells

BioEssays, Volume 47, Issue 11, November 2025.
Primary cilia are developmentally essential subcellular signaling compartments. However, many differentiated cells lack primary cilia, and cilia disassembly in these tissue contexts has been largely overlooked. We highlight several pathways for primary cilia loss and examine how changes in ciliation states could contribute to diverse pathologies ...
Carolyn M. Ott, Saikat Mukhopadhyay
wiley   +1 more source

Case Report: 3D-CISS and PC-MRI in the diagnosis and surgical planning of hydrocephalus secondary to presumptive lateral aperture obstruction in a dog. [PDF]

Front Vet Sci
Tauro A, Kurihara M, Macri J, Early P, Mariani CL, Olby NJ, Muñana KR, Lewis MJ, Sjalander-Dillenbeck L.   +8 more
europepmc   +1 more source

A case of meningitis tuberculosa presenting hypothermia and hydrocephalus.

, 1996
井桁 之総, 菅 貞郎, 柚木 和太, 佐藤 周三, 美原 盤   +4 more
openalex   +2 more sources

Neurocutaneous Melanosis in Children and Adults With Clinical, Radiological, and Pathogenic Evaluation: Case Report and Review of the Literature

Clinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT Neurocutaneous melanosis (NCM) is a rare, non‐inherited disease characterized by the presence of giant congenital melanocytic nevi (CMN) or multiple CMN, and it is often associated with meningeal melanosis or meningeal melanoma. This report presents two representative cases of NCM: one involving a 6‐year‐old female patient and the other ...
Yinghua Ji, Keya Zhi, Han Yang, Xiangli Meng, Jin Wang, Jinling Xie, Yong Tan, Ping Lu, Yana Zhang   +8 more
wiley   +1 more source