Results 61 to 70 of about 199,619 (340)

Retinoic Acid Reprograms Mast Cells Toward a Proinflammatory State to Enhance Antitumor Immunity

Advanced Science, EarlyView.
Proinflammatory mast cells represent an MHC‐IIhigh, cytokine‐producing mast cell subset associated with improved survival and enhanced responses to anti‐PD‐1 therapy. Retinoic acid drives their polarization, enabling antigen uptake and presentation, and T cell recruitment and activation, collectively promoting adaptive anti‐tumor immunity.
Lizao Zhang, Siqi Ren, Yuhui Li, Rongxi Chen, Ling Qiu, Yongmei Tan, Suling Chen, Huiqian Wu, Lianxi Mai, Xiao Tan, Xin Liu, Peisheng Liang, Shijia Kuang, Liansheng Wang, Jingkang Liu, Jintao Li, Yanyan Li, Qiuping Xu, Yongzhi Su, Yuehai Luo, Binyan Wu, Zijing Huang, Haotian Cao, Qunxing Li, Jinsong Li, Tianjun Lan   +25 more
wiley   +1 more source

Prediction of shunt dependent hydrocephalus following aneurysmal subarachnoid hemorrhage “algorithm based management”

Nepal Journal of Neuroscience, 2018
Aneurysmal subarachnoid hemorrhage (aSAH) is a devastating disease with a high rate of mortality and permanent morbidity. An important neurologic complication is hydrocephalus reported to range from 6 to 67% while only 10-20% of them will require ...
Shikher Shrestha , Suresh Bishokarma , Subash Lohani , Suresh Sapkota, Sangita Thapa, Dinesh Nath Gongal   +5 more
doaj   +1 more source

Outcomes of the 2019 hydrocephalus association workshop, "Driving common pathways: extending insights from posthemorrhagic hydrocephalus"

Fluids and Barriers of the CNS, 2023
The Hydrocephalus Association (HA) workshop, Driving Common Pathways: Extending Insights from Posthemorrhagic Hydrocephalus, was held on November 4 and 5, 2019 at Washington University in St. Louis. The workshop brought together a diverse group of basic,
Jason K. Karimy, Jessie C. Newville, Cameron Sadegh, Jill A. Morris, Edwin S. Monuki, David D. Limbrick, James P. McAllister II, Jenna E. Koschnitzky, Maria K. Lehtinen, Lauren L. Jantzie   +9 more
doaj   +1 more source

A Closer Look at the Global Management of Spina Bifida: The Implementation of Endoscopic Third Ventriculostomy in the Treatment of Spina Bifida-Related Hydrocephalus in Africa [PDF]

, 2018
Spina bifida, specifically myelomeningocele, is a debilitating neural tube defect that affects patients and families throughout the world. Traditional management and treatment methods are described, followed by an explanation of why this is often ...
Burckart, Caryssa
core   +1 more source

Intracranial haemorrhage in a dobermann puppy with von Willebrand's disease [PDF]

, 1995
Neurological examination of a lethargic, ataxic 12-week-old dobermann revealed decreased conscious proprioception in all its limbs. Haematological examination revealed a low platelet count.
Dunn, J.K., Dunn, K.J., Herrtage, M.E., Nicholls, P.K.   +3 more
core   +2 more sources

Myelomeningocele-associated hydrocephalus: nationwide analysis and systematic review.

Neurosurgical Focus, 2019
OBJECTIVE Myelomeningocele (MMC), the most severe form of spina bifida, is characterized by protrusion of the meninges and spinal cord through a defect in the vertebral arches.
D. McCarthy, D. Sheinberg, E. Luther, Heather J. McCrea   +3 more
semanticscholar   +1 more source

Intelligent Supportive System for People with Profound Intellectual and Multiple Disabilities

Advanced Intelligent Systems, EarlyView.
A holistic INSENSION system is developed—a novel intelligent decision support system leveraging state‐of‐the‐art noninvasive audio‐visual sensor technologies together with machine learning algorithms and expert knowledge, to detect and interpret behaviors and communications (nonverbal signals—NVSs) of people with PIMD in challenging real‐world ...
Gašper Slapničar, Michał Kosiedowski, Arkadiusz Radziuk, Erik Dovgan, Torsten Hammann, Meike Engelhardt, Christin Kupitz, Carmen Campomanes‐Alvarez, Dorota Janczewska, Peter Zentel, Mitja Luštrek   +10 more
wiley   +1 more source

FGF2 is expressed in human and murine embryonic choroid plexus and affects choroid plexus cell behaviour [PDF]

, 2008
Background Although fibroblast growth factor (Fgf) signalling plays crucial roles in several developing and mature tissues, little information is currently available on expression of Fgf2 during early choroid plexus development and whether Fgf2 directly ...
Ferretti, P., Greenwood, S., Swetloff, A., Terasaki, T., Wade, A.   +4 more
core   +3 more sources

Clinical Presentation of the Longest Reported Living Individual With Bent Bone Dysplasia—FGFR2‐Related

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The FGFR2 gene, encoding the FGFR2 protein, plays a crucial role in embryonic cell development, particularly in bone tissue. Bent Bone Dysplasia (BBD), FGFR2‐related (MIM# 614592), is a rare severe skeletal dysplasia characterized by craniofacial differences, reduced bone mineral density, and bowed long bones.
Cheyenne Bates, Pardeep Gill, Matthew Choi, Frances Mahon, Blake Yarascavitch, Audrey Lim, Resham Ejaz   +6 more
wiley   +1 more source

Simple Patient-Based Transmantle Pressure and Shear Estimate From Cine Phase-Contrast MRI in Cerebral Aqueduct [PDF]

, 2012
From measurements of the oscillating flux of the cerebrospinal fluid (CSF) in the aqueduct of Sylvius, we elaborate a patient-based methodology for transmantle pressure (TRP) and shear evaluation.
Balédent, Olivier, Bardan, Gérald, Plouraboué, Franck, Zagzoule, Mokhtar   +3 more
core   +2 more sources