Evaluation of antihypertensive efficacy of Losartan + Hydrochlorthiazide versus Telmisartan + Hydrochlorthiazide in patients with stage 1 or stage 2 hypertension: a randomized controlled trial [PDF]
Background: Cardiovascular disease (CVD) is the most common contributor of morbidity and mortality in underdeveloped and developing countries including the South Asian countries (including India and Pakistan). Amongst the cluster group of CVDs, Hypertension (HTN) represents the most common cardiovascular risk factor.
Manreet Singh Sekhon +4 more
openaire +3 more sources
Inguinal hernia repair in an elderly patient with moderate aortic stenosis under sole epidural anesthesia: A case report. [PDF]
Key Clinical Message In resource limited settings, epidural anesthesia can be a safe option for elderly patients with aortic stenosis for lower abdominal surgeries as the hemodynamic changes are known to be less as compared to spinal or general anesthesia.
Devkota S, Thapa Y.
europepmc +2 more sources
Drug-induced vasculitis: Thiazide or the COVID-19 vaccine, which one is guilty? A case report and literature review. [PDF]
Drug‐induced vasculitis should be considered in the setting of vasculitis after the initiation of a new medication or the administration of COVID‐19 vaccines. Abstract A middle‐aged woman with a history of COVID‐19 vaccine administration and valve replacement surgery was admitted with bilateral palpable purpuric lesions in the lower extremities and ...
Hekmat M +3 more
europepmc +2 more sources
Severe Late-Onset Drug-Induced Immune Thrombocytopenia Following IFN β-1a Treatment: A Case Report of a 52-Year-Old Woman with Relapse-Remitting Multiple Sclerosis. [PDF]
Interferon β‐1a (IFNβ1a) is considered safe in relapsing‐remitting multiple sclerosis (RRMS). Drug‐induced thrombocytopenia (DITP) is a rare but underreported adverse event that is often confused with other causes of thrombocytopenia. We report the case of a 52‐year‐old woman who developed limb and oral mucosa petechiae and hematochezia, 10 years after
Cisarovsky C +4 more
europepmc +2 more sources
The association of smoothness index of central blood pressure with ambulatory carotid femoral pulse wave velocity after 20-week treatment with losartan in combination with amlodipine versus hydrochlorothiazide. [PDF]
Objectives: The aim of this study was to identify associations between the smoothness index of central SBP (CSBP) and changes of ambulatory carotid femoral pulse wave velocity in response to 20-week treatments with losartan and amlodipine vs.
Shin J +19 more
europepmc +3 more sources
Mind the gap in kidney care: translating what we know into what we do. [PDF]
Abstract Historically, it takes an average of 17 years to move new treatments from clinical evidence to daily practice. Given the highly effective treatments now available to prevent or delay kidney disease onset and progression, this is far too long. The time is now to narrow the gap between what we know and what we do.
Luyckx VA +18 more
europepmc +3 more sources
Abstract Objectives To describe the incidence and outcomes of pulmonary oedema in women with severe maternal outcome during childbirth and identify possible modifiable factors through audit. Methods All women with severe maternal outcome (maternal deaths or near misses) who were referred to Tygerberg referral hospital from health facilities in Metro ...
Anke Heitkamp +9 more
wiley +1 more source
Toward mandatory health insurance in low‐income countries? An analysis of claims data in Tanzania
Abstract Many low‐income countries are in the process of scaling up health insurance with the goal of achieving universal coverage. However, little is known about the usage and financial sustainability of mandatory health insurance. This study analyzes 26 million claims submitted to the Tanzanian National Health Insurance Fund (NHIF), which covers two ...
Kathrin Durizzo +6 more
wiley +1 more source
Low plasma taurine levels in English cocker spaniels diagnosed with dilated cardiomyopathy
Objectives The aims of this study were to evaluate taurine levels in English cocker spaniels with dilated cardiomyopathy and assess their survival time and natural progression of their disease. Materials and Methods Retrospective comparison of English cocker spaniels with dilated cardiomyopathy phenotype with and without taurine deficiency at the ...
M. Basili +5 more
wiley +1 more source
Abstract Objective The study sought to assess the prognostic impact of treatment with mineralocorticoid receptor antagonists (MRA) on recurrences of ventricular tachyarrhythmias in implantable cardioverter‐defibrillator (ICD) recipients with systolic heart failure (HF). Background Data regarding the outcome of patients with ventricular tachyarrhythmias
Tobias Schupp +15 more
wiley +1 more source

