Comparative effectiveness of antihypertensive drugs prescribed in Ethiopian healthcare practice: A pilot prospective, randomized, open label study. [PDF]
BACKGROUND:Previous research has been highly suggestive that patients of African ancestry are less responsive to beta-blockers and angiotensin converting enzyme inhibitors.
Hayelom Gebrekirstos Mengesha +12 more
doaj +1 more source
Influence of Tablet Splitting on Content Uniformity of Lisinopril/Hydrochlorthiazide Tablets
Dose-related adverse effects of medications are a major problem in modern medical practice. The “correct” dose, based on drug company guidelines in package inserts, may not be correct for many patients. Tablet splitting or dividing has been an accepted practice for many years as a means of obtaining the prescribed dose of medication.As model tablets ...
Edina, Vranić, Alija, Uzunović
openaire +3 more sources
FORMULATION AND EVALUATION OF GASTRORETENTIVE FLOATING BIOADHESIVE TABLETS OF HYDROCHLORTHIAZIDE
Objective: Floating bioadhesive tablets of hydrochlorothiazide were developed to prolong gastric residence time leading to an increase in drugbioavailability where here a combination of floating and bioadhesion mechanism is combined.Methods: Tablets are prepared by direct compression technique using polymers xanthan gum, carbopol 974 P, HPMC K15M, HPMC
Ramu Bandameedi, Shanmunga Pandiyan P
openaire +2 more sources
DESIGN OF ORALLY DISINTEGRATING TABLET OF HYDROCHLORTHIAZIDE AND IT’S EVALUATION
The aim of present work was to show the effect of various superdisintegrant on the disintegration time and in vitro drug release rate. In this study, an attempt had been made to prepare orally disintegrating t ablets of the Hydrochlorthiazide using co - processed super disintegrant following direct compression method.
C. S Magdum, V. R Salunkhe, D. A Meher
openaire +1 more source
Azilsartan: Current Evidence and Perspectives in Management of Hypertension
Hypertension continues to be global pandemic with huge mortality, morbidity, and financial burden on the health system. Unfortunately, most patients with hypertension would eventually require two or more drugs in combination to achieve their target blood pressure (BP).
Akshyaya Pradhan +3 more
wiley +1 more source
Effects of Hydrochlorothiazide on Tenofovir Disoproxil Fumarate-Induced Nephrotoxicity in Rats
Tenofovir disoproxil fumarate, a nucleotide reverse transcriptase inhibitor utilized for the treatment of hepatitis B virus and human immunodeficiency virus infections; and is now one of the most widely used antiretroviral drug.
Iman G.Al-Rakhat, Nada N.Al-Shawi
doaj +1 more source
Emphysematous cystitis: An unusual disease of the Genito-Urinary system suspected on imaging [PDF]
Emphysematous cystitis is a rare disease entity caused by gas fermenting bacterial and fungal pathogens. Clinical symptoms are nonspecific and diagnostic clues often arise from the unanticipated imaging findings.
Ravi K Bobba +3 more
core +1 more source
Abstract EFSA was asked by the European Commission to update the Scientific Opinion on methodological principles and scientific methods to be taken into account when establishing Reference Points for Action (RPAs) for non‐allowed pharmacologically active substances in food of animal origin.
EFSA Panel on Contaminants in the Food Chain (EFSA CONTAM Panel) +27 more
wiley +1 more source
Angiotensiin II retseptorite blokaatorid (antagonistid) ja nende koht tänapäeva kardioloogias [PDF]
Reniin-angiotensiinsüsteem (RAS) on organismi üks olulisemaid vererõhku, vee- ja elektrolüütide tasakaalu reguleerivaid fermentsüsteeme. Angiotensiin II (A II) on selle ensümaatilise kaskaadi tähtsaim lõpp-produkt. RASi blokeerimine ravimitega on andnud
Lapidus, Ilja
core +2 more sources
Calcium Unresponsive Hypocalcemic Tetany: Gitelman Syndrome with Hypocalcemia
Introduction. Gitelman’s syndrome (GS) is autosomal recessive renal tubular disorder characterized by hypokalemia, hypomagnesemia, hypocalciuria, metabolic alkalosis, and hyperreninemic hyperaldosteronism. It is usually associated with normal serum calcium.
Madhav Desai +3 more
wiley +1 more source

