Protocol for the specialist supervised individualised multifactorial treatment of new clinically diagnosed type 2 diabetes in general practice (IDA):a prospective controlled multicentre open-label intervention study [PDF]
, 2017 IntroductionWe present the protocol for a multifactorial intervention study designed to test whether individualised treatment, based on pathophysiological phenotyping and individualised treatment goals, improves type 2 diabetes (T2D) outcomes.Methods and
Beck-Nielsen, Henning +7 more
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Ventricular arrhythmia and torsade de pointe: Dose limiting toxicities of the MDR-modulator S9788 in a phase I trial [PDF]
, 2017 Background: S9788 is a triazineaminopiperidine derivative capable of reversing multidrug resistance (MDR) in vitro. In preclinical models S9788 was several fold more potent MDR inhibitor than verapamil or cyclosporine.
Bastian, G. +10 more
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Hot Melt Extrusion: Highlighting Physicochemical Factors to Be Investigated While Designing and Optimizing a Hot Melt Extrusion Process [PDF]
, 2018 Hot-melt extrusion (HME) is a well-accepted and extensively studied method for preparing numerous types of drug delivery systems and dosage forms. It offers several advantages: no solvents are required, it is easy to scale up and employ on the industrial
Casadidio, Cristina +3 more
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Pharmaco-economical analysis of Russian QUADRIGA Study data
Кардиоваскулярная терапия и профилактика, 2006 Aim. To assess antihypretensive effect quality and duration for ACE inhibitor spirapril (Quadropril®; daily dose 6 mg) among arterial hypertension (AH) patients, in real-world out-patient clinical settings. Material and methods.
A. A. Kuprina, Yu. B. Belousov
doaj
Pharmaceutica Analytica Acta, 2011 Two simple, accurate, novel, safe and precise methods were developed for the simultaneous estimation of poorly water-soluble drugs Eprosartan Mesylate and Hydrochlorthiazide in tablet dosage form using 2M Sodium acetate and 8M Urea solution (50:50% W/V) as a mixed hydrotropic solution.
Ruchi Jain, Vinod Sahu, Nilesh Jain
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PROLOG study: main results and guidance for further action
Кардиоваскулярная терапия и профилактика, 2006 The article contains main results of PROLOG study, that compared effectiveness of controlled arterial hypertension therapy in step-wise antihypertensive treatment scheme: ACE inhibitor, spirapril, with addiction, if necessary, of diuretic ...
S. Yu. Martsevich +4 more
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Evaluasi Ketepatan Pemilihan Obat Dan Outcome Terapi Pada Pasien Hipertensi Rawat Jalan Di Rumah Sakit Umum Daerah Dr. Moewardi Tahun 2013 [PDF]
, 2013 Terapi non farmakologis yang dilakukan kerap tidak cukup bagi banyak orang penderita hipertensi, sehingga diperlukan terapi farmakologis menggunakan obat anti hipertensi.
, Tri Yulianti, M.Si., Apt. +1 more
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LIQUID CHROMATOGRAPHIC METHOD FOR THE SIMULTANEOUS QUANTITATIVE DETERMINATION OF CANDESARTAN CILEXETIL AND HYDROCHLORTHIAZIDE IN PHARMACEUTICAL DOSAGE FORMS [PDF]
, 2012 A simple and sensitive RP-HPLC method was developed and validated for the determination of Candesartan cilexetil and Hydrochlorthiazide in pharmaceutical dosage forms. The separation of components was achieved on a SHIMADZU Hypersil ODS-C18 column (250 ×
A., Narendra +2 more
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Is the fixed-dose combination of telmisartan and hydrochlorothiazide a good approach to treat hypertension? [PDF]
, 2007 Blockade of the renin-angiotensin system with selective AT1 receptor antagonists is recognized as an effective mean to lower blood pressure in hypertensive patients.
Burnier, M., Maillard, M.P.
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Effect of Diuretic Medication and Coffee Consumption on Serum Uric Acid Levels: A Review of Literature [PDF]
, 2023 Various factors like diet, medications, beverages, and congenital conditions have shown to have their effect on uric acid levels. Hyperuricemia (serum uric acid level > 6.8mg/dL) is detrimental to health and is an independent risk factor for all cause
Yasser Jamaan Mohammed Al-Ghamdi , Mohammed Abdullah Ali Alsloli , Zakaria Yahya Ali Alamri
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