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Hydrocortisone in Severe Community-Acquired Pneumonia.

New England Journal of Medicine, 2023
BACKGROUND Whether the antiinflammatory and immunomodulatory effects of glucocorticoids may decrease mortality among patients with severe community-acquired pneumonia is unclear.
P. Dequin   +37 more
semanticscholar   +1 more source

Comparative Effectiveness of Fludrocortisone and Hydrocortisone vs Hydrocortisone Alone Among Patients With Septic Shock.

JAMA Internal Medicine, 2023
Importance Patients with septic shock may benefit from the initiation of corticosteroids. However, the comparative effectiveness of the 2 most studied corticosteroid regimens (hydrocortisone with fludrocortisone vs hydrocortisone alone) is unclear ...
N. Bosch   +5 more
semanticscholar   +1 more source

Combination of vitamin C, thiamine and hydrocortisone added to standard treatment in the management of sepsis: results from an open label randomised controlled clinical trial and a review of the literature

Infectious Diseases, 2020
Background: Combination of vitamin C, hydrocortisone and thiamine have recently been used in sepsis but data of efficacy are conflicting and no data are available from developing countries. We sought to study the effect of addition of this combination to
Saleem J. Wani   +8 more
semanticscholar   +1 more source

Preinterventional hydrocortisone sustains the endothelial glycocalyx in cardiac surgery

Clinical Hemorheology and Microcirculation, 2018
BACKGROUND: Patients undergoing cardiac surgery commonly develop systemic inflammation associated with tissue edema, which impairs outcome. One main pathomechanism leading to the edema is the deterioration of the endothelial glycocalyx, a key component ...
F. Brettner   +7 more
semanticscholar   +1 more source

Hydrocortisone therapy for patients with septic shock.

New England Journal of Medicine, 2008
C. Sprung   +14 more
semanticscholar   +1 more source

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