Results 221 to 230 of about 257,235 (317)

Helical opto-thermoviscous flows drive out-of-plane rotation and particle spinning in a highly viscous micro-environment. [PDF]

Light Sci Appl
Nan F, Liao W, Puerta A, Spiegelberg J, Erben E, Mikut R, Allgeier S, Wegener M, Lauga E, Kreysing M.   +9 more
europepmc   +1 more source

Extreme Polaritonic Interactions in a Room‐Temperature Designable Sub‐Nanocavity Quantum Electrodynamic Platform

Advanced Science, EarlyView.
 A nanoparticle‐cluster‐on‐mirror (NPcoM) serves as a functionally deterministic sub‐nanocavity that emulates picocavities, enabling extreme light–matter interactions and polaritonic phenomena. ABSTRACT Pushing nanoscale optical confinement to its ultimate limits defines the regime of nano‐cavity quantum electrodynamics (nano‐cQED), where light‐matter ...
Huatian Hu, Xin Shu, Zhiwei Hu, Di Zheng, Ruiqian Zhang, Ximin Cui, Wei Dai, Xiang Lan, Xiaobo Han, Wen Chen, Hongxing Xu   +10 more
wiley   +1 more source

Electrophoresis of an Oil Drop in a Charged Polymer Gel Medium: Coupled Effects of Drop Electrohydrodynamics and Gel Electroosmosis. [PDF]

Gels
Ohshima H.
europepmc   +1 more source

Early Detection and Inhibition of Post‐Surgical Cancer Recurrence by Synthetic Extracellular Vesicles

Advanced Science, EarlyView.
An implantable hydrogel is designed to hold gene transfection agents engineered to turn early recurrent tumor cells into generators of synthetic EVs. These synthetic EVs can express engineered miR‐26a (E‐miR‐26a) for highly sensitive detection and PD‐1 (a PD‐L1‐blocking agent) for therapeutic intervention, thereby enabling early detection and ...
Junli Zhang, Wenjia Chang, Ruolin Hu, Peiyan Su, Qin Zhou, Yanan Li, Zhenzhong Zhang, Kaixiang Zhang   +7 more
wiley   +1 more source

Rapid-manufacturing and cost-effective single-layer microfluidic device for high-throughput three-dimensional hydrodynamic focusing. [PDF]

Microsyst Nanoeng
Yan R, Wei S, Weng Y, Li R, Jin Y, Liu X, Hou J, Xu Y, Li S, Wang D, Ye H, Liu S, Lei C.   +12 more
europepmc   +1 more source

Brain and Liver Dual‐Targeting Oridonin Nanoparticles to Enhance Aβ Clearance for Alzheimer's Disease Therapy

Advanced Science, EarlyView.
We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong, Wenting Hui, Sai Qiao, Qifeng Ji, Miao Liu, Bangle Zhang, Daozhou Liu, Yumei Wu, Siyuan Zhou   +8 more
wiley   +1 more source

From Clogging Mitigation to Clogging Acceleration: Particle Deposition Under Oscillatory Flow in Microfluidic Porous Media. [PDF]

Transp Porous Media
Okaybi W, Roman S, Soulaine C.
europepmc   +1 more source

ESCRT‐Mimetic Nanodegrader Targets STING for Anti‐Inflammatory Therapy

Advanced Science, EarlyView.
A nanoplatform‐enabled targeted protein degradation strategy is presented to regulate aberrant STING signaling. STING‐ATTEC induces selective autophagic degradation of STING via formation of a STING–ATTEC–LC3 ternary complex, while the cationic FA‐LNP+ system enhances LC3 generation and targeted delivery. Together, this synergistic approach efficiently
Fuyuan Zhou, Qiming Zhai, Zhihao Yao, Qing Li, Yan Yang, Si Wang, Chao Huang, Liangjing Xin, Tao Chen, Jinlin Song   +9 more
wiley   +1 more source

Gold Nanoparticle Complexes with PAMAM Dendrimers for In Vitro Cancer Cytotoxicity Assessment: Synthesis via Ascorbic Acid Reduction. [PDF]

Molecules
Kołodziejczyk AM, Karwowski BT, Grala M.   +2 more
europepmc   +1 more source

Microglia‐Targeted Biomimetic Tetrahedral Framework Nucleic Acid Nanovesicles for Synergistic Treatment of Sepsis‐Associated Encephalopathy

Advanced Science, EarlyView.
Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi, Qiuxia Gao, Wenying Wang, Bin Li, Yukun Chen, Zhijun Yao, Yujie Li, Junrui Li, Na Li, Gong Gu, Zhimin Hou, Mengyuan Yang, Ruilin Zhang, Hongju Yang, Yuhui Liao, Hongyi Lei   +15 more
wiley   +1 more source