Results 131 to 140 of about 23,891 (308)

Combining Radiation‐Treated Tumor Vaccines With Mn‐MOF Nanoadjuvants to Amplify Radiation Induced Anti‐Tumor Immune Responses

open access: yesAdvanced Science, EarlyView.
Radiotherapy‐treated tumor membranes are integrated with Mn‐MOF nanoadjuvants to generate Mn@RM, a lymph node‐draining nanovaccine that delivers radiotherapy‐remodeled antigenic components. Mn@RM enhances dendritic cell activation, amplifies T cell‐mediated antitumor immunity, and synergizes with radiotherapy and PD‐1 blockade for combination cancer ...
Yiyu Wang   +8 more
wiley   +1 more source

NIR‐II‐Trackable LYTACs Phyto‐Nanotheranostics for Source‐Microenvironment Dual‐Track ROS Regulation in Acute Gouty Arthritis

open access: yesAdvanced Science, EarlyView.
The TPR‐LYTACs nanomaterial offers a dual‐pathway strategy for precise gouty arthritis treatment by targeting and degrading the ROS‐producing enzyme NOX2 inside macrophages while its antioxidant core clears accumulated ROS outside. This “source inhibition and microenvironment scavenging” approach, guided by NIR‐II imaging, effectively controls local ...
Jian Zhang   +15 more
wiley   +1 more source

Hydrostatic and Hydrodynamic Bearing on Grinding Machine [PDF]

open access: yes
In recent years, the demand for hydrostatic bearing application has been increasing due to the possibilities and advantages they offer. Advances in the understanding of hydrostatic lubrication and the improvement of computer technology have opened ...
Kandemir Sani   +2 more
core   +1 more source

An Edible Biohybrid Platform Accomplishes In Situ Fenton‐Mediated Enteral Nanoplastics Aging and Excretion

open access: yesAdvanced Science, EarlyView.
An edible biohybrid platform triggers nanoplastics (NPs) aging and agglomeration by in situ generating hydroxyl radicals within the intestine. The enlarged NPs are unable to penetrate the intestine and are subsequently excreted. Simultaneously, probiotic biofilms reinforce the intestinal barrier.
Su Zhou   +4 more
wiley   +1 more source

An Investigation of Acoustic Emission Responses of a Self Aligning Spherical Journal Bearing [PDF]

open access: yes, 2011
High power industrial machinery such as steam turbines and large pumps use journal bearings as rotor supports because this type of bearing is a high load carrying capacity.
Gu, Fengshou   +8 more
core  

HYDRODYNAMIC LUBRICATION OF A RADIAL BEARING OF INCREASED BEARING CAPACITY WITH BARREL ROTATION UNEVENNESS

open access: yesAdvanced Engineering Research, 2010
In this paper we present the calculation method of the gliding radial bearing similar to the circular one in the presence of unevenness on the barrel surface.
K.S. AKHVERDIEV   +2 more
doaj  

A Wireless 3D Magneto‐Mechanical Stimulation Platform Drives In Situ Chondrogenic Commitment of Endogenous MSCs

open access: yesAdvanced Science, EarlyView.
An intracellular magneto‐mechanical platform utilizing MSC‐targeted nanomotors is developed. After intra‐articular delivery, these nanomotors target endogenous BMSCs and are actuated within lysosomes to execute trans‐planar rotational‐bouncing motions under a rotating‐fluctuating 3D magnetic field, generating amplified mechanical stimulation.
Zhenguang Li   +7 more
wiley   +1 more source

RNF138‐Mediated Ubiquitination and Degradation of NS5 Restricts Tick‐Borne Encephalitis Virus Infection

open access: yesAdvanced Science, EarlyView.
Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Jialiang Sun   +6 more
wiley   +1 more source

Toward Nano‐Nutritional Medicine: A Remotely Activated Trans‐Vaccenic Acid‐Based Lipid Nanoparticles for Enhancing Immune Checkpoint Blockade Therapy

open access: yesAdvanced Science, EarlyView.
Eutectic mixtures from trans‐vaccenic acid (TVA) and stearic acid, which served as phase‐change material to encapsulate IR780, forming NIR‐responsive nanoparticles. IR780@TVA LNPs induce photothermal therapy and initiate adaptive anti‐tumor immunity.
Kang Liu   +12 more
wiley   +1 more source

ANALYSIS OF HYDRODYNAMIC JOURNAL BEARING WITH AN AXIAL GROOVE [PDF]

open access: yes, 2017
In rotordynamic, hydrodynamic journal bearings are one of the most crucial components due to their wide demand and applications in different industries ranging from small applications, such as those supporting rotating grinders for dentistry, to large ...
MOHAMMAD PURE, SHAHAB HAMDAVI
core  

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