Results 51 to 60 of about 5,865,704 (298)
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Modelling of the coupling hydrodynamic transfer for a gas-liquid countercurrent flow on a wavy surface [PDF]
, 2003 This paper concerns laminar countercurrent gas–liquid flow over a wavy wall column, in the case of a falling liquid film. The modelling concerns the coupling of hydrodynamic and heat and mass transfer for an absorption as an example of application.
Prevost, Michel +2 more
core +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
A hydrodynamic study of deep-water mooring characteristics
, 2014 This paper discusses hydrodynamic study of deep-water mooring ...
Lin, Zi, Sayer, Philip
core +3 more sources
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Journal of Marine Science and EngineeringThe rapid expansion of large-scale aquaculture has created a demand for more efficient and sustainable farming systems. Among these, land-based circular tank aquaculture is emerging as a key solution due to its high efficiency, scalability, and effective
Yanfei Wu +6 more
doaj +1 more source
Hydrodynamic Characteristics Analysis of Amphibious HydrofoilVehicle Based on LBM-LES Method
Hangkong gongcheng jinzhan, 2019 At present, research on the aerodynamics and hydrodynamic characteristics of a amphibious hydrofoil vehicle at home and abroad is still at exploration and development stage.
Feng Huanhuan +3 more
doaj +1 more source
Elasto-Hydrodynamic Lubrication Effect in Thrust-Slide Bearings of Scroll Compressors [PDF]
, 2012 This paper presents the concept of the Elasto-Hydrodynamic Lubrication (EHL) effect for the thrust slide-bearings in scroll compressors, which accounts for the superior lubrication characteristics of these bearings.
Anami, Keiko +4 more
core
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source