Results 151 to 160 of about 147,583 (292)

Multi‐Level Confinement Single‐Molecule Charge Transfer Activated PRET for Near‐Infrared Targeted Cell Imaging

open access: yesAdvanced Science, EarlyView.
The cascade supramolecular assembly of charge‐transfer arrays not only triggered a topological transformation from nanofiber to nanorod and vesicles, but also promoted single‐molecule phosphorescent resonance energy transfer, expanding phosphorescence emission at 500 nm to near‐infrared delayed fluorescence emission at 650 nm with a lifetime of 11.20 ...
Zhuo Lei   +5 more
wiley   +1 more source

Extreme Kinetic Stability and RNase Resistance of Human Telomerase RNA G‐Quadruplexes Overcome by DHX36 Helicase

open access: yesAdvanced Science, EarlyView.
The RNA G‐quadruplexes formed at the 5'‐end of the RNA component of human telomerase possess extreme slow unfolding rate, rendering them resistant to nuclease degradation. The helicase DHX36 overcame this kinetic barrier and significantly reduced the folded fraction.
Qun Luo   +5 more
wiley   +1 more source

Development of a Numerical Model of a Bio-Inspired Sea Lion Robot. [PDF]

open access: yesBiomimetics (Basel)
Kadapa S   +4 more
europepmc   +1 more source

Semiconducting Polymer Nanoparticles Enable Light‐Controlled Bidirectional Modulation of Nitric Oxide in Endothelial Cells

open access: yesAdvanced Science, EarlyView.
Bimodal modulation of nitric oxide in endothelial cells is achieved by light‐sensitive polymer nanoparticles. In dark, P3HT/PEDOT:PSS NPs boost intracellular ·NO, upregulate both endothelial and induced nitric oxide synthase, and drive a metabolic shift toward glycolysis.
Camilla Marzuoli   +12 more
wiley   +1 more source

Flow transports extracellular lipid-anchored proteins across the surface of living COS-7 cells. [PDF]

open access: yesBiophys J
Sasidharan S   +7 more
europepmc   +1 more source

NIR‐II Imaging‐Guided Photothermal Activation of a TRPV4‐Targeted Nanoplatform Delivering Cycloastragenol to Promote Microglia Reprogramming and α‐Synuclein Clearance in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
ABSTRACT Current therapies for Parkinson's disease (PD) fail to concurrently address α‐synuclein (α‐syn) aggregation and microglia‐mediated neuroinflammation. Herein, we engineer a near‐infrared‐II (NIR‐II) phototheranostic nanoplatform, CAG/FD1080@MM‐aTRPV4, for synergistic regulation of microglial function and real‐time monitoring of PD pathology. We
Hsuan Lo   +9 more
wiley   +1 more source

Redefining the Health Risk of Battery Materials Through a Biologically Transformed Metal Mixture

open access: yesAdvanced Science, EarlyView.
Inhaled NCM particles undergo lysosomal degradation, releasing complex ion mixtures that induce systemic impact. The impact is determined by a critical balance between antagonistic Ni‐Co interactions and synergistic Mn effects. To capture these complexities in risk assessment, we develop an IAI model, ensuring a more accurate quantitative risk ...
Ze Zhang   +11 more
wiley   +1 more source

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